HOMEWORK#7

Sequence comparison / Homology search

• due on 5/28

• David Liu, a student in department of Life Sciences, was bitten by a snake in the backyard of life science building. He was so angry! Thus, he killed the snake and purified several toxins from its venoms. He sequenced one of the toxin, got this sequence:

1 L K C N K L V P L F Y K T C P A G K N L C Y K M F M V A T P

31 K V P V K R G C I D V C P K S S L L V K Y V C C N T D R C N

(1) Is this a new toxin? Please help him to identify this toxin.

(2) Can you find proteins that share sequence homology with this toxin? Show them in multiple alignment form.

(3) Please predict its secondary structure.

(4) Please show its charge distribution.