Publications

1.         Chang HY, Guerrero I, Lake R, Pellicer A, D'Eustachio P. (1987) Mouse N-ras genes: organization of the functional locus and of a truncated cDNA-like pseudogene. Oncogene Research 1:129-136.

2.         Drivas G, Massey R, Chang HY, Rush MG, and D¡ŠEustachio P (1991) Ras-like genes and gene families in the mouse. Mammalian Genomes 1: 112-117

3.         Peng HL, Wang PY, Wu CL, Chiu CT, and Chang HY (1991) Molecular epidemiology of Klebsiella pneumoniae. Chinese Journal of Microbiology and Immunology 24:264-271

4.         Peng HL, Wang PY, Wu CM, Hwang DC, and Chang HY (1992) Cloning sequencing and heterologous expression of the Klebsiella pneumoniae gene encoding an FAD-independent acetolactate synthase. Gene 117:125-130

5.         Peng HL, Fu TF, Liu SF, and Chang HY (1992) Cloning and expression of the Klebsiella pneumoniae galactose operon. Journal of Biochemistry 112:604-608

6.         Peng HL and Chang HY (1993) Cloning of a human liver UDPglucose pyrophosphorylase cDNA by complementation of the bacterial galU mutation. FEBS letter 329:153-158.

7.         Peng HL, Hsieh MJ, Zao CL, and Chang HY (1994) Nucleotide sequence and expression in Escherichia coli of Klebsiella pneumoniae deaD gene. Journal of Biochemistry 115:409-414

8.         Deng WL, Chang HY, and Peng HL (1994) Characterization of the acetoin utilization system in Klebsiella pneumoniae: cloning, sequencing and expression analysis of the aco operon. Journal of Bacteriology 176:3517-3535

9.         Duggleby RG, Peng HL, and Chang HY (1996) An improved assay for UDPglucose pyrophosphorylase and other enzymes that have a nucleoside triphosphate or diphosphate product. Experientia, 52:568-572.

10.     Duggleby RG, Chao YC, Huang CG, Peng HL, and Chang HY (1996) Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetics differences between human muscle and liver cDNA expressed in Escherichia coli. European Journal of Biochemistry 235:173-179

11.     Chang HY, Deng WL, Lee JH, Fu TF, and Peng HL (1996) Virulence and outer membrane properties of a Klebsiella pneumoniae galU mutant. Microbial Pathogenesis 20:255-261

12.     Chang HY, Peng HL, Chao YC, and Duggleby RG (1996) The importance of conserved residues in human liver UDPglucose pyrophosphorylase. European Journal of Biochemistry 236:723-728.

13.     Skurat AV, Peng HL, Chang HY, Cannon JF, and Roach PJ. (1996) Rate-limiting steps in the biosynthesis of glycogen in COS cells. Archive of Biochemistry and Biophysics 328:283-288.

14.     Peng HL, Deng WL, Yang YH, and Chang HY (1996) Identification and characterization of the acoD gene encoding a dihydrolipoamide dehydrogenase of the Klebsiella pneumoniae acetoin dehydrogenase system. Journal of Biochemistry 119:1118-1123.

15.     Cheng SD, Peng HL, and Chang HY (1997) Localization of human muscle form of UDPglucose pyrophosphorylase encoding gene on 2p13-14. Genomics 39:414-416.

16.     Peng HL, Yang YH, Deng WL, and Chang HY (1997) Identification and characterization of AcoK, a regulatory gene of Klebsiella pneumoniae aco operon. Journal of Bacteriology 179:1497-1504.

17.     Peng HL, Lou MD, Chang ML, and Chang HY (1998) cDNA cloning and expression analysis of the human UDPglucose dehydrogenase. Proceedings of National Science Council, ROC 22:166-172

18.     Huang YC. Lin TY. Peng HL. Wu JH. Chang HY. Leu HS. (1998) Outbreak of Candida albicans fungaemia in a neonatal intensive care unit. Scandinavian Journal of Infectious Diseases. 30:137-42.

19.     Peng HL, Cheng SD, Lee JH, and Chang HY (1999) Identification of a novel family of human Rab-like small GTP binding proteins. Proceedings of National Science Council, ROC 23:1-6

20.     Chang HY, Hsiao SR, and Peng HL (1999) Characterization of MdcR, a transcription factor of the malonate decarboxylase operon in Klebsiella pneumoniae. Journal of Bacteriology 181-2302-2306

21.     Chang HY, Huang HC, Lee JH, and Peng HL (1999) Characterization of a putative Pseudomonas UDPglucose pyrophosphorylase. Proceedings of National Science Council, ROC  23:74-84

22.     Huang YC, Lin TY, Leu HS, Peng HL, Wu JH and Chang HY (1999) Outbreak of Candida parapsilosis fungemia in neonatal intensive care units: clinical implications and genotyping analysis. Infection 27:97-102

23.     Leu YJ, Hu BS, Wu WL, Lin YH, Chang HY, and Shi ZY (2000) Identification of a major cluster of Klebsiella pneumoniae isolates from patients with liver abscess in Taiwan. Journal of Clinical Microbiology, 38: 412-414.

24.     Lai YC, Yang SL, Peng HL, and Chang HY. (2000) Identification of genes present specifically in a virulent strain of Klebsiella pneumoniae. Infection and Immunity 68:7149-7151

25.     Lai YC, Peng HL, and Chang HY. (2001) Identification of in vivo induced genes in Klebsiella pneumoniae. Infection and Immunity 69:7140-7145.  

26.     Wardwell SA, Yang YT, Chang HY, San KY, Rudolph FB, Bennett GN. (2001) Expression of the Klebsiella pneumoniae CG21 acetoin reductase gene in Clostridium acetobutylicum ATCC 824. Journal of Industrial Microbiology and Biotechnology 27:220-227.

27.     Tsai CL, Tsai CL, Tse KP, Chang HY and Chang YS (2002) LMP1-mediated downregulation of E-cadherin through hypermethylation of the E-cadherin promoter. Proc. Natl. Acad. Sci.USA.99:10084-10089.

28.     Lai YC, Peng HL and Chang HY (2003) RmpA2, an activator of capsule biosynthesis in Klebsiella pneumoniae CG43, regulates K2 cps gene expression at the transcriptional level. Journal of Bacteriology 185:788-800.

29.     Lai YC, Lin JT, Yang SL, Chang HY, and Peng HL. (2003) Characterization of kvgAS operon encoding a novel two-component system in Klebsiella pneumoniae CG43. FEMS Microbiology Letters 218:121-126.          

30.     Chien CM, Cheng, JL, Chang WT, Tien MH, Wu WY, Chang YH, Chang HY and Chen ST. (2003) Cell phenotype analysis using a cell-fluid based microchip with high sensitivity and accurate quantitation. Journal of Chromatography B Analytical Technology of Biomedical and Life Science 795:1-8.

31.     Fang CY, Chang YS, Chow KP, Yu JS, Chang HY. (2004) Construction and Characterization of monoclonal antibodies specific to Epstein-Barr virus latent membrane protein 1. Journal of Immunological Methods 287: 21¡V 30

32.     Chen YT, Chang HY, Lai YC, Pan CC, Tsai SF, and Peng HL. (2004) Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43. Gene 337:189-98

33.      Wang S-R, Chang J-T, Lin M-S, Chiang C-Y, and Chang HY (2004) Establishing the Reactivity of Monoclonal Antibodies against Porcine Endogenous Retrovirus Envelope Protein.  Intervirology 47:93-101

34.     Chiang CY, Chang JT, Wang SR, and Chang HY. (2004) Characterization of a monoclonal antibody specific to the Gag protein of porcine endogenous retrovirus and its application in detecting the virus infection. Virus Research 108(1-2): 139-48

35.     Chen YT, Chang HY, and Peng HL. (2004) Evolutionary analysis of the two-component systems in Pseudomonas aeruginosa PAO1. Journal of Molecular Evolution 59(6):725-37. 

36.     Pan YR, Fang CY, Chang YS, and Chang HY. (2004). Analysis of Epstein-Barr virus gene expression upon phorbol ester and hydroxyurea treatment by real-time quantitative PCR. Archives of Virology 150(4):755-70

37.     Chien CM, Cheng JL, Chang WT, Tien MH, Tsao CM,  Chang YH, Chang HY, JHsieh JH,  Wong CH, and Chen ST. (2004). Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood. Bioorganic Medicinal Chemistry 12(21):5603-9

38.     Hsu FR, Chang HY,  Lin YL, Tsai YT, Peng HL, Chen YT,  Cheng CY, Shih MY,  Liu CH, Chen CF. 2005 AVATAR: A database for genome-wide alternative splicing event detection through analysis of large scale ESTs and mRNAs. Bioinformation 1(1): 16-18

39.     Vatsyayan J, Peng HL, Chang HY. 2005 Analysis of human UDP-glucose dehydrogenase gene promoter: identification of an Sp1 binding site crucial for the expression of the large transcript. Journal of Biochemistry. 137(6):703-9

40.     Lin YC, Lu CL, Tang CY, Chang HY, (2005) An efficient algorithm for sorting by block interchange and its application to the evolution of Vibrio species. Journal of Computation Biology 12(1):102-12.

41.     Ho CT, Lin RZ, Chang HY, Liu CH. 2005. Micromachined Electrochemical T-switches for Cell Sorting Applications. Lab-on-a-chip. 5(11):1248-58

42.     Vatsyayan J, Lee SJ, Chang HY. 2005 Effects of xenobiotics  and peroxisome proliferator receptor- alpha on the human UDPglucose dehydrogenase gene expression. Journal of Biochemical and Molecular Toxicology 19(5):279-88 

43.     Liu, C.-H., Hsu, F.R., Chang, H.Y., Shia, W.-C., Peng, H.-L., Chen, Y.T., Lin, Y.-L., Tsai, Y.-T. (2005). Comparative analysis of alternative splicing events in human and mouse. WSEAS Transactions on Information Science and Applications 3 (9), pp. 1772-1776

44.     Lin RZ, Chou LF, Chien CM, Chang HY (2006). Dynamics of hepatoma spheroid formation: roles of E-cadherin and beta-integrin. Cell and Tissue Research 324(3):411-22

45.     Vatsyayan J, Lin CT, Peng HL, Chang HY (2006) Identification of a cis-acting element responsible for negative regulation of the human UDP-glucose dehydrogenase gene expression. Bioscience Biotechnology Biochemistry 70(2): 401-10     

46.     Ho CT, Lin RZ, Chang HY, Liu CH (2006). Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap. Lab-on-a-Chip. 6(6):724-34

47.     Lin RZ, Ho CT, Liu CH, Chang HY. (2006) Dielectrophoresis based-cell patterning for tissue engineering. Biotechnology Journal. 1(9):949-57

48.     Chang BJ, Huang YJ, Chan JH, Hsu L, Peng HL, Chang HY, Yew TR, Liu CH, Chi S. (2006) Measurement of the adhesive force between a single Klebsiella pneumoniae type 3 fimbria and collagen IV using optical tweezers. Biochem. Biophy. Res. Commun. 10;350(1):33-8

49.     Chiang CY, Chou LF, Pan YR, Fang CY, Wang SR, Yang CY, Chang HY. (2007) Two functional epitope determinants on porcine endogenous retrovirus envelope protein interacted with neutralizing-antibody combining sites. Virology 10;361(2):364-71

50.     Hung RJ, Lin RZ, Lin CT, Peng HL, Vatsyayan J. Chang HY (2006). Comparative analysis of two UDPglucose dehydrogenases in Pseudomonas aeruginosa PAO1. Journal Biological Chemistry Apr 18; [Epub ahead of print]

51.     Fang CY, Chiang CY, Pan YR, Tse KP, Chang YS, Chang HY (2006) Modulation of Epstein-Barr Virus Latent Membrane Protein 1 activity by intrabodies. Intervirology 50(4):254-263 

52.     Liu PF, Chang WC, Wang YK, Munisamy SB, Hsu SH MS; Chang HY, Wu SH, Pan RL.(2007) Differential regulation of Ku gene expression in etiolated mung bean hypocotyls by auxins. BBA - Gene Structure and Expression Apr 10; [Epub ahead of print]

53.     Liu PF, Wang YK, Chang WC, Chang HY, Pan RL. (2008) Regulation of Arabidopsis thaliana Ku genes at different developmental stages under heat stress. Biochim Biophys Acta. Gene Structure and Expression 2008 May 11. [Epub ahead of print]

54.     Chow KP, Wu CC, Chang HY, Chang C, Chang YS. (2008) A simplified tumour model established via Epstein-Barr Virus encoded nasopharyngeal carcinoma derived-oncogene latent membrane protein-1 in immunocompetent mice. Laboratory Animals 42:193-203 

55.     Yang CW, Yang YN, Liang PH, Chen CM, Chen WL, Chang HY, Chao YS, Lee SJ. (2007) Novel small-molecule inhibitors of transmissible gastroenteritis virus. Antimicrobial Agents Chemotherapy Nov;51(11):3924-31.

56.     Chang,JH, Hocheng H, Chang HY, and Shih A, (2007) Metal removal rate of Thiobacillus thiooxidans without pre-secreted metabolite. Journal of Material Processing Technology Available online 29 November 2007

57.      Kuo MC. Chou LF, Chang HY (2008) Evolution of exceptionally large genes in prokaryotes. Journal of Molecular Evolution 66(4):333-49

58.     Hsu JL, Chen HC, Peng HL, and Chang HY (2008) Characterization of the histidine-containing phosphotransfer protein B-mediated multi-step phosphorelay system in Pseudomonas aeruginosa PAO1. Journal of Biological Chemistry 283(15):9933-44 

59.     Chen TC, Liu SC, Huang PN, Chang HY, Chern JH, and Shih SR. (2008) Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants. Journal of Biomedical Science 15(3):291-300

60.     Lu YC, Chuang YS, Chen YY, Shu AC, Hsu HY, Chang HY, and Yew TR. (2008) Bacteria Detection Utilizing Electrical Conductivity.  Biosensors and Bioelectronics 23(12):1856-61

61.     Liu PF, Wang YK, Chang WC, Chang HY, Pan RL. (2008) Regulation of Arabidopsis thaliana Ku genes at different developmental stages under heat stress. Biochim Biophys Acta. Gene Structure and Expression 1779(6-7): 402-7

62.     Lin RZ and Chang HY. (2008) Advances in three-dimensional multicellular spheroid culture for biomedical research. Biotechnology Journal Oct;3(9-10):1285

63.     Lin RZ, Chu WC, Chiang CC, Lai CH, and Chang HY (2008) Magnetic reconstruction of three-dimensional tissues with complex architectures from multicellular spheroidal organoids. Tissue Engineering 14(3):197-205

64.     Shu AC, Wu CC, Peng HL, and Chang HY, Yew, TR (2008) Evidence of DNA Transfer through F-pilus Channel during Escherichia coli Conjugation. Langmuir 24(13):6796-802  

65.     Liu YJ, Yao DJ, Lin HC, Chang WY, Chang HY. (2008) DNA ligation of ultramicro volume using an EWOD microfluidic system with coplanar electrodes. 2008 J. Micromech. Microeng. 18 045017 (accepted for publication)

66.     Liu YJ, Yao DJ, Chang HY, Liu CM, Chen C. (2008) DNA detection with multi-layers quantum dots labeling for rapid detection of Escherichia coli O157:H7. Biosensors and Bioelectronics 24(4):558-65

67.     Pan YR, Chang YS, Vatsyayan, J, Chang, HY.  (2008) Upregulation of UDPglucose dehydrogenase gene by Epstein-Barr virus LMP2A. Cellular Microbiology. 10(12):2447-60 

68.     Hsu JL Chang HY (2008) Importance of ATP binding sites in Acok, a transcription factor controlling acetoin catabolism in Klebsiella pneumoniae.  Biochem Biophys Res Commun. 7;376(1):121-7.

69.     Liu KL, Wu CC, Huang YJ, Peng HL, Chang HY, Chang P, Hsu L, and Yew TR, 2008 Novel microchip for in situ TEM imaging of living organisms and bio-reactions in aqueous conditions. Lab-on-a-Chip. 8(11):1915-21.

70.     Lee HJ, Chang HY, Peng HL, 2008 Important residue of a phosphomannose isomerase in Pseudomonas aeruginosa PAO1. FEBS Letter. 582(23-24): 3479-83

71.     Chen, YY, Wu CC; Hsu JL, Peng HL, Chang HY, Yew TR. 2009 Surface Rigidity change of Escherichia coli after filamentous bacteriophage infection Langmuir  25(8):4607-14

72.     Chou LF, Peng HL, Yang YC, Kuo MC, Chang HY. 2009 Localization and characterization of VVA0331, a 489-kDa RTX-like protein, in Vibrio vulnificus YJ016. Archives of Microbiology 191(5):441-50.

73.     Chen TC, Chang HY, Lin PF, Chern JH, Hsu JT, Chang CY, Shih SR. 2009 Novel Antiviral Agent DTriP-22 Targets RNA-dependent RNA Polymerase of Enterovirus 71. Antimicrobial Agents Chemotherapy 53(7):2740-7.

74.     Tu YC, Lu MC, Chiang MK, Huang SP, Peng HL, Chang HY, Jan MS, Lai YC. (2009) Genetic requirements for Klebsiella pneumoniae-induced liver abscess in an oral infection model. Infection and Immunity 77(7):2657-71

75.     Yan, K.H., Yao, C.J., Chang, HY., Lai, G.M., Cheng, A.L., and Chuang, S.E. (2010). The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. Molecular Carcinogenesis 235-246.

76.      Lee HJ, Ho MR, Hsu CY, Huang MS, Peng HL, Chang HY (2010) Enhancing ATP-based bacteria and biofilm detection by enzymatic pyrophosphate regeneration. Analytical Biochemistry 399(2):168-73

77.      Hsu CL, Shiung YY, Lin BL, Chang HY, Chang TW. (2010) Accumulated immune complexes of IgE and omalizumab trap allergens in an in vitro model. International Immunopharmacology 10(4):533-9.

78.      Chen JB, Wu PC, Hung AF, Chu CY, Tsai TF, Yu HM, Chang HY, Chang TW. (2010) Unique epitopes on C epsilon mX in IgE-B cell receptors are potentially applicable for targeting IgE-committed B cells. Journal of Immunology 184(4):1748-56.

79.     Cheng HY, Chen YS, Wu CY, Chang HY, Lai YC, Peng HL. 2010 RmpA regulation of capsular polysaccharide biosynthesis in Klebsiella pneumoniae CG43. Journal of Bacteriology, 192(12):3144-58.

80.     Puttaswamy SV, Sivashankar S, Chen RJ, Chin CK, Chang HY, Liu CH. 2010 Enhanced cell viability and cell adhesion using low conductivity medium for negative dielectrophoretic cell patterning. Biotechnology Journal 5(10):1005-15.

81.     Wang TP, Pan YR, Fu CY, Chang HY. 2010 Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells. Experimental Cell Research. 15;316(17):2893-902.

82.     Lin RZ, Wang TB, Chuang YJ, Chang HY 2010. Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species. Journal of Cell Physiology 2010 Nov 10. [Epub ahead of print]

83.     Hsu FY, Chou LF, Hor LI, Chang HY (2010) A human single-chain variable fragment targeting to Vibrio vulnificus RtxA toxin. Journal of Microbiological Methods 84(1):94-100.

84.     Chen FR, Chan CH, Huang YR, Liu GG, Peng HL, Chang HY, Liu CH, Hsu L (2011) Structural and Mechanical Properties of Klebsiella pneumoniae Type 3 Fimbriae. Journal of Bacteriology Jan 14. [Epub ahead of print]

85.     Liao YC, Huang TW, Chen FC, Charusanti P, Hong JS, Chang HY, Tsai SF,Palsson BO, Hsiung CA. (2011) An experimentally validated genome-scale metabolic reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228. Journal of Bacteriology.  [Epub ahead of print]

86.     Fu CY, Lin JY, Chu WC, Chang HY. (2011) A simple cell patterning method using magnetic particle-containing photosensitive poly (ethylene glycol) hydrogels. Tissue Engineering (in Revision)

87.     Lee HJ, Ho MR, Tseng CS, Hsu CY, Huang MS, Peng HL, Chang HY (2010) Exponential ATP amplification through simultaneous regeneration from AMP and pyrophosphate for luminescence detection of bacteria. Analytical Biochemistry

88.     Bhuwan, M., Lee, H. J., Peng, H. L., Chang, HY. (2011) Histidine phosphotransfer protein (HptB) mediates swarming motility by partner switching signaling in Pseudomonas aeruginosa, PAO1. Journal of Biological Chemistry 287(3):1903-14.

89.     Chuang, Y. H., Chang, Y. T., Liu, K. L, Chang, HY., Yew, T. R. (2011) Electrical impedimetric biosensors for liver function detection. Biosensor Bioelectronics 15;28(1):368-72

90.     Lee, Y. Z., Huang, C. W., Yang, C. W., Hsu, H. Y., Kang, I. J., Chao, Y. S., Chen, I. S., Chang, HY., Lee, S. J. (2011) Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the Formosan Tylophora ovata. Planta Medica (17):1932-8

91.     Wu, P. H., Hsu, J. J., Chiang, T. W., Hsieh, Y. C., Chang, HY., Chang, S. L. and Chen, C. J. (2011) Purification, crystallization and preliminary X-ray crystallographic analysis of the receiver and stalk domains (PA3346RS) of the response regulator PA3346 from Pseudomonas aeruginosa PAO1. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 67: 937-940.

92.     Tu MC, Chang YT, Kang YT, Chang HY, Chang P, Yew TR. (2012) A quantum dot-based optical immunosensor for human serum albumin detection. Biosensors Bioelectronics 34(1):286-90

93.     Chan CH, Chen FJ, Huang YJ, Chen SY, Liu KL, Wang ZC, Peng HL, Yew TR, Liu CH, Liou GG, Hsu KY, Chang HY, Hsu L. (2012) Identification of protein domains on major pilin MrkA that affects the mechanical properties of Klebsiella pneumoniae type 3 fimbriae. Langmuir. 28(19):7428-35.

94.     Chou, HT, Wang TP, Lee, CY, Tai NH, Chang HY. (2013) Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells. Material Science and Engineering C- Materials for biological applications. 33(2):989-9953

95.     Hao HC, Chang HY, Wang TP, Yao DJ. (2012) Detection of cells captured with antigens on shear horizontal surface-acoustic-wave sensors. Journal of Laboratory Automation [Epub ahead of print]

96.     Chen NY, Hung AF, Lin CJ, Chen JB, Chu HM, Yu HM, Chang HY, Chang TW. (2012) Manipulating mIgD-expressing B cells with anti-migis-£_ monoclonal antibodies. Molecular Immunology 53(3):187-197. [Epub ahead of print]

97.     Lee YZ, Yang CW, Hsu HY, Qiu YQ, Yeh TK, Chang HY, Chao YS, Lee SJ. (2012) Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: exploration of the role of tylophorine e ring on biological activity. J Med Chem. 2012 Dec 13;55(23):10363-77

98.     Yang CW, Lee YZ, Hsu HY, Wu CM, Chang HY, Chao YS, Lee SJ. (2013) c-Jun-mediated anti-cancer mechanisms of tylophorine. Carcinogenesis 34(6):1304-14.

99.     Yan KH, Lee LM, Hsieh MC, Yan MD, Yao CJ, Chang PY, Chen TL,Chang HY, Cheng AL, Lai GM, Chuang SE. (2013) Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells. Oncology Report 30(3):1497-505

100.  Ho CT, Lin RZ, Chen RJ, Chin CK, Gong SE,Chang HY, Peng HL, Hsu L, Yew TR, Chang SF, Liu CH. (2013) Liver-cell patterning Lab Chip: mimicking the morphology of liver lobule tissue. Lab Chip. 13(18):3578-87

101.  Huang TW, Lam I, Chang HY, Tsai SF, Palsson BO, Charusanti P. (2013) Capsule deletion via a lamda-Red knockout system perturbs biofilm formation and fimbriae expression in Klebsiella pneumoniae MGH 78578. BMC Research Notes. 2014 Jan 8;7(1):13. [Epub ahead of print]

102.  Chen TJ, Wu JK, Chang YC, Fu CY, Wang TP, Lin CY, Chang HY, Chieng CC, Tzeng CY, Tseng FG. (2014) High-efficiency rare cell identification on a high-density self-assembled cell arrangement chip. Biomicrofluidics.12; 8(3): 036501.

103.  Fu CY, Tseng SY, Yang SM, Hsu L, Liu CH, Chang HY (2014) A microfluidic chip with a U-shaped microstructure array for multicellular spheroid formation, culturing and analysis. Biofabrication. 6(1):015009.

104.  Chou HT, Lee HJ, Lee CY Tai NH, Chang HY (2014) Highly durable anodes of microbial fuel cells using a reduced graphene oxide/carbon nanotube-coated scaffold. Bioresource Technology, Available online 16 July

105.  Santra TS, Chang HY, Wang PC, Tseng FG. (2014) Impact of pulse duration on localized single-cell nano-electroporation. Analyst. 7;139(23):6249-58.

106.  Wu WH, Punde TH, Shih PC, Fu CY, Wang TP,Hsu L, Chang HY, Liu CH. (2014) A capillary-endothelium-mimetic microfluidic chip for the study of immune responses. Sensors & Actuators: B. Chemical

107.  Dong GC, Kuan CY, Subramaniam S, Zhao JY, Sivasubramaniam S, Chang HY, Lin FH. (2015) A potent inhibition of oxidative stress induced gene expression in neural cells by sustained ferulic acid release from chitosan based hydrogel. Material Science Engineering C Material Biological Application. 49:691-9.

108.  Hung LY, Wang CH, Che YC, Fu CY, Chang HY, Wang K and Lee GB. (2015) Screening of aptamers specific to colorectal cancer stem cells and colorectal cancer cells by utilizing On-chip Cell-SELEX. Scientific Reports,

109.  Chen LY, Wu PH, Guan HH, Fun HK, Chang HY, Chen CJ. (2015) Purification, crystallization and preliminary X-ray crystallographic analysis of the phosphatase domain (PA3346PD) of the response regulator PA3346 from Pseudomonas aeruginosa PAO1. Acta Crystallogr F Structure Biology Communication 71(Pt 4):434-7.

110.  Chou HT, Fu CY, Tai NH, Chang HY,* (2015) An ultrasensitive sandwich type electrochemiluminescence immunosensor for triiodothyronine detection using silver nanoparticle-decorated graphene oxide as a nanocarrier. Biosensors and Bioelectronics 71:476-482

111.  Chen YC, Wen KP, Chou HT, Chang HY, Tai NH* (2015) Accumulation and toxicity of intravenously-injected functionalized graphene oxide in mice. Journal of Applied Toxicology

112.  Che YJ, Wu HW, Hung LY, Liu CA, Chang HY, Wang K, Lee GB. (2015) An integrated microfluidic system for screening of phage-displayed peptides specific to colon cancer cells and colon cancer stem cells. Biomicrofluidics. 15;9(5): 054121

113.  Chen YT, Goudar VS, Wu RG, Hsieh HY, Yang CS, Chang HY, Lee GB , Ho CM, Tseng FG. (2016) A UV-sensitive hydrogel based combinatory drug delivery chip (UV gel-Drug Chip) for cancer cocktail drug screening. RSC Advances 6   (50) 44425-44434

114.  Santra TS, Chen CW, Chang HY, Tseng FG. (2016) Dielectric passivation layer as a substratum on localized single-cell electroporation. RSC Advances 6, 10979-10986

115.  Lo YL, Shen L, Chang CH, Bhuwan M, Chiu CH, Chang HY. (2016) Regulation of Motility and Phenazine Pigment Production by FliA Is Cyclic-di-GMP Dependent in Pseudomonas aeruginosa PAO1. PLoS One. 13;11(5):e0155397.

116.  Yang CW, Lee YZ, Hsu HY, Shih C, Chao YS, Chang HYLee SJ (2017) Targeting Coronaviral Replication and Cellular JAK2 Mediated Dominant NF-£eB Activation for Comprehensive and Ultimate Inhibition of Coronaviral Activity. Scientific Reports 22;7(1):4105. doi: 10.1038/s41598-017-04203-9.