授課教師: 吳夙欽 (生科二館 R510, TEL: 574-2906)
授課時間: 星期二 (AM 9:10 - PM 12:00)
授課地點: 生科一館 R117
Gary Walsh and Denis Headon, Protein Biotechnology, John Wiely & Sons (1994)
30% (mid-term), 30% (presentation), 40% (final report)
02/23---------- Introduction
03/02---------- Scope of protein biotechnology( Chapter 1 )
03/09---------- Industrial enzymes and immobilized techniques
03/16---------- Protein sources( Chapter 2 )
03/23---------- Mid-term
03/30---------- Protein expression system - I
04/06---------- Spring vacation
04/13---------- Protein expression system - II
04/20---------- Metabolic engineering
04/27---------- Mammalian and insect cell cultures
05/04---------- Optimal fed-batch processfor mAb production
05/11---------- Therapeutic mAB and bioreactor design
05/17---------- Metabolic ratio and statistical experimental design
05/24---------- Downstream processing
05/31---------- Special considerations of therapeutic proteins ( Chapter 4 )
06/07---------- Manufacturing process for recombinant factor IX
06/14---------- Presentation
06/22---------- Presentation and final report submission