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Original Research Papers

1. Chen, H.-H., Hsu, C.-H., Chang, Y.-C. and Wei, H.-H. (1981) Mossbauer spectroscopic studies of trifluorostannate (ll) in frozen aqueous solutions. Radiochem. Radioanal. Letters 59, 167-171.

2. Scott, R.D., Chang, Y-C., Graves, D.J. and Metzler, D.E. (1983) NMR study of 5-fluoro-pyridoxal phosphate-containing cytosolic aspartate aminotransferase, in ¡§Chemical and biochemical aspects of vitamin B6 catalysis¡¨, vol. 2, R.Alan ed., Liss Inc., New York,pp.249-257.

3. Graves, D.J., Soman, G., Hurst, M. and Chang, Y.-C. (1983) Involvement of guanidinogroup in anion-binding sites and in enzyme-catalyzed covalent modification reactions, Current Topics in Cellular Regulation 24, 181-190.

4. Chang, Y,-C., McCalmont, T. and Graves, D.J. (1983) Functions of 5¡¥-phosphate group of pyridoxal 5¡¦-phosphate in phosphorylase: A study using pyridoxal reconstituted enzyme as a model system. Biochemistry 22, 4987-4993.

5. Soman, G., Chang, Y.-C. and Graves, D.J. (1983) Effects of oxyanions of early transition metals on rabbit skeletal muscle phosphorylase. Biochemistry 22, 4993-4998.

6. Arus, C., Chang, Y.-C. and Barany, M. (1985) N-acetylaspartate as an intrinsic thermometer for H-1 NMR of sliced brain.  J. Magn.Reson. 63, 376-379.

7. Barany, M., Chang, Y-C., Arus, C., Rustan, T. and Frey. W.H. (1985) Increased glycerol-3-phosphocholine in postmortem Alzheimer¡¥s brain.  Lacet I, 517.

8. Barany, M., Chang, Y.-C. and Arus, C. (1985) Effects of halothane on the natural abundance C-13 NMR spectra of excised rat brain.  Biochemistry 24, 7911-7917.

9. Barany, M., Arus, C. and Chang, Y.-C. (1985) Natural abundance C-13 NMR of brain. Magn. Reson. Med.  2, 289-295.

10. Arus, C., Chang, Y.-C. and Barany, M. (1985) The separation of phosphocreatine from creatine and pH determination in frog muscle by natural abundance C-13 NMR. Biochem. Biophys. Acta.  844, 91-93.

11. Chang, Y.-C., Arus, C. and Barany, M. (1985) Characterization of the broad resonance in P-31 NMR spectra of excised rat brain.  Physiol. Chem. Phys. Med. NMR 17, 143-154.

12. Scott, R.D., Chang, Y.-C., Graves, D.J. and Metzler, D.E. (1985) Studies of 6-fluoropyridoxal and 6-fluoropyridoxamine 5¡¥-phosphate in cytosolic aspartate aminotransferase. Biochemistry 24, 7668-7681.

13. Chang, Y.-C. and Graves, D.J. (1985) Use of 6-fluoroderivatives of pyridoxal phosphate in the study of coenzyme function in glycogen phosphorylase.  J. Biol. Chem. 260, 2709-2714.

14. Chang, Y.-C., Scott, R.D. and Graves, D.J. (1986) Function of pyridoxal-5¡¥-phosphate in glycogen phosphorylase: F-19 NMR and kinetic studies of phosphorylase reconstituted with 6-fluoropyridoxal and 6-fluoropyridoxal phosphate.  Biochemistry 25, 1932-1939.

15. Gottlieb, D.I., Chang, Y.-C. and Schwob, J. (1986) Monoclonal antibodies of glutamic acid decarboxylase.  Proc, Natl. Acad. Sci. USA 83, 8808-8812.

16. Chang, Y.-C., Soman, G. and Graves, D.J. (1987) Identification of an enzymatic activity that hydrolyzes protein bound ADP-ribose in skeletal muscle.  Biochem. Biophys. Res. Comm. 139, 932-939.

17. Chang, Y.-C., Scott R.D. and Graves, D.J. (1987) Function of pyridoxal-5¡¥-phosphate in glycogen phosphorylase: A model study using 6-fluoro-5¡¦-deoxypyridoxal and 5¡¥-deoxypyridoxal reconstituted enzyme.  Biochemistry 26, 360-367.

18. Chang, Y.-C. and Gottlieb, D.I. (1988) Characterization of the protein purified with monoclonal antibodies to glutamic acid decarboxylase.  J. Neurosci. 8, 2123-2130.

19. Hon, Y.-S., Chang, Y.-C. and Gong, M.-L. (1990) Efficient enantioselective syntheses of (4R)-substituted (2S)-glutamic acids.  Heterocycles 31, 191-196.

20. Chang, Y.-C., Hon, Y.-S. and Chow, W.-Y. (1990) Solubilization and characterization of glutamate binding sites from porcine brain.  Neurochem. Int. 16, 173-185.

21. Hon, Y.-S., Chang, Y.-C. and Gong, M.-L. (1991) The studies of a-alkylation of N-tert-BOC-5(S)-tert-butyldimethylxymethyl-2-pyrrolidinones. Bull. Inst. Chem. Academia Sinica.  38, 23031.

22. Chang, Y.-C., Lin, I.-H., Lee, Y.-H. and Leng, C.-H. (1991) Solubilization, characterization and partial purification of AMPA, quisqualate, kainate-sensitive L-[3H]glutamate binding sites from porcine brain synaptic junctions.  J. Neurochem. 57, 1921-1926.

23. Tong, C.-K., Pang, M.-P. and Chang, Y.-C. (1992) Characterization of L-glutamate and kainate binding sites of the brain of a freshwater fish Telapilia monsanbica. Neuroscience 49, 237-246.

24. Chang, Y.-C. (1992) Efficient precipitation and accurate quantitation of detergent-solubilized membrane proteins.  Anal. Biochem. 205, 22-26.

25. Chang, Y.-C., Hon, Y.-S., Chow, W.-Y., Lin, T.-A., Jan, P.-Y. and Wang, C.-M. (1993) Study of stereoselectivity of L-glutamate receptors by synthetic 4(R)-and 4(S)-substituted L-glutamate analogues.  Brain Res. 604, 86-89.

26. Chang, Y.-C., Chiu, S.-J. and Kao, K.-P. (1993) Beta-N-methylamino-L-alanine induces behavioral changes and a decrease of glutamate receptors.  Chinese J. Physiol. 36, 79-84.

27. Wu, T.-Y. and Chang, Y.-C. (1994) Hydrodynamic and pharmacological characterization of putative AMPA/kainate-sensitive L-glutamate receptors solubilized from porcine brain.  Biochem. J. 300, 365-371.

28. Tyan, S.-H., Chang, S.-M., Gean, P.-W., Hon, Y.-S. and Chang, Y.-C. (1996) 4(R)- and 4(S)- (5-phenylpentyl)-glutamic acids attenuate excitatory postsynaptic potential on hippocampus without inhibiting postsynaptic NMDA and AMPA receptors.  Chinese J. Physiol. 39, 131-137.

29. Chang, Y.-C., Wu, T.-Y., Li, B.-F., Gao, L.-H., Liu, C.-Y. and Wu, C.-L. (1996) Purification and biochemical characterization of AMPA/kainate-sensitive L-glutamate receptors of porcine brain.  Biochem. J. 319, 49-57.

30. Wu, T.-Y., Liu, C.-Y. and Chang, Y.-C. (1996) A study of the oligomeric state of AMPA-preferring glutamate receptors in the synaptic junctions of porcine brain.  Biochem. J. 319, 331-339.

31. Tyan, S.-H., Sue, T.-Y., Hon, Y.-S., Gean, P.-W. and Chang, Y.-C. (1997) A novel NMDA receptor antagonist protects against N-methyl-D-aspartate- and glutamate-induced neurotoxicity in the goldfish retina.  Eur. J. Pharmacol. 321, 171-179.

32. Lai, S.-L., Ling, S.-C., Kuo, L.-H., Shu, Y.-C., Chow, W.-Y. and Chang, Y.-C. (1998)  Characterization of granular particles isolated from postsynaptic densities.  J. Neurochem. 71, 1694-1701.

33. Chang, S.-M., Wu, Y.-M., Chang, Y.-C., Hsu, Y.-C., Hsu, H.Y., Chen, C.-C. and Chow, W.-Y. (1998)  Molecular and electrophysiological characterization of fGluR3, an ionotropic glutamate receptor subunit of a teleost fish.  Mol. Brain Res. 57, 211-220.

34. Lai, S.-L., Chiang, S.-F., Chen, I.-T., Chow, W.-Y. and Chang, Y.-C. (1999) Inter-protein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density.  J. Neurochem.73, 2130-2138.

35. Hon, Y.S., Chang, Y.-C. and Chu, K.P. (2000)  Synthesis of 3-substituted ¡VL-glutamic acid analogues for neuroexcitatory activity studies.  J. Chinese Chem. Soc. 47, 91-102.

36. Sui, C.-W., Chow, W.-Y. and Chang, Y.-C. (2000) Effects of disulfide bonds formed during isolation process on the structure of the postsynaptic density.  Brain Res. 873, 268-273.

37. Lin, Y.-C., Huang, Z.-H., Jan, I.S., Yeh, C.-C., Wu, H.-J., Chou, Y.C. and Chang, Y.-C. (2002) Development of excitatory synapses in cultured neurons dissociated from the cortices of rat embryos and rat pups at birth. J. Neurosci. Res. 67, 484-493.

38. Srisalam, S., Wang, H.-M., Kumar, T.K.S., Rajalingam, D., Sivaraja, V., Sheu, H.-S., Chang, Y.-C. and Yu, C. (2002) Amyloid-like fibril formation in an all b-barrel protein involves the formation of partially structured intermediate(s). J. Biol. Chem. 277, 19027-19036.

39. Jan, H.-H., Chen, I.-T., Tsai, Y.-Y. and Chang, Y.-C. (2002) Structural roles of the zinc ions bound to the postsynaptic density. J. Neurochem. 83, 525-534.