DNA Recognition by Eucaryotic Transcription Factors


  • much more complex
  • less well understood
  • 3 classes of RNA polymerases
  • RNA polymerase I -> genes encoding ribosomal RNAs
  • RNA polymerase II -> genes encoding messenger RNAs
  • RNA polymerase III -> genes encoding transfer RNAs

  • The transcription elements of a eucaryotic structural gene extend over a large region of DNA

  • core or basal promoter elements
  • promoter proximal elements
  • distal enhancer element

  • Model for transcriptional activation -

     


    | Next |