LS4524 Biophysical Chemistry II
Instructor:
P.
C. Lyu (2/17/04 - 3/19/04)
Instructor:
T.
H. Lin (3/23/04 - 4/27/04)
Instructor:
Y.
J. Sun (4/30/04 - 6/01/04)
Tuesday and Friday 8:30 am - 9:50 am
Three Examinations - 35 % each
LS Bldg. II room 105
2/17
Introduction
2/20
Introduction of Protein Structure
2/24
Introduction of Protein Structure
2/27
Introduction of Spectroscopy (10)
3/02
Infrared (IR), Ultraviolet (UV) and visible light spectroscopy
3/05
CD (10)
3/09
NMR (10)
3/12
NMR (10)
3/16
Mass
3/19
Exam. I
3/23 Intermolecular and
intramolecular forces (9)
3/26
Molecular dynamics simulation (9)
3/30 Wave mechanics
(9)
4/02
no Class
4/06 Schrodinger's
equation (9)
4/09 Particle
in a box (9)
4/13 Hydrogen
atom (9)
4/16 Molecular
orbitals (9)
4/20 Boltzmann
distribution (11)
4/23 Partition
function and application (11)
4/27
Exam. II
4/30 Molecular Motion and Transport Properties
(6)
5/04 Molecular Motion and Transport Properties
(6)
5/07 Sample separation and purification
(6)
5/11 Fluorescence (10)
5/14 X-ray diffraction (12)
5/18 Macromolecular Structure determination
by X-ray diffraction (12)
5/21 Macromolecular Structure determination
by X-ray diffraction (12)
5/25 Electron and Neutron diffraction (12)
5/28 Microscopy & Surface plasmon resonance
(BIACORE)
6/01 Exam. III
Core Course toward the Understanding of Physical Basis of the Life Sciences
I ) Undergraduate
Biophysical Chemistry (6) - Concepts of Physical Chemistry in Biology
Physical Chemistry - Principles and applications in Biological
Sciences
Tinoco, Jr., Sauer, Wang. 3rd Ed.
II ) Graduate
Physical Biochemistry (3) - Principles and Techniques
Text- Principle of Physical Biochemistry van Holde, Johnson,
Ho(1998)
Reference - Molecular Biophysics Daune (1999)
Structural Biology (3) - Function and Informatics
Text - Structure and Mechanism in Protein Science Alan Fersht
(1999).
Reference - Introduction to Protein Structure Branden &
Tooze (1999)
Special Topics in Structural Biology (3) - Current Trends
Office hour
Mon. 9:30 - 11:30 and by appointment (PCL LSII 306)