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LOCUS       461863         81 aa                              01-JUN-1994
DEFINITION  CARDIOTOXIN PRECURSOR.
ACCESSION   461863
PID         g461863
DBSOURCE    SWISS-PROT: locus CX1_NAJSP, accession Q02454
            class: standard.
            created: Feb 1, 1994.
            sequence updated: Feb 1, 1994.
            annotation updated: Jun 1, 1994.
            xrefs: genbank accession L04640, gi: 213375, gi: 266266
            xrefs (non-sequence databases): HSSP P01444, PROSITE PS00272
KEYWORDS    VENOM; CYTOTOXIN; CARDIOTOXIN; SIGNAL.
SOURCE      Naja sputatrix.
  ORGANISM  Naja sputatrix
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Lepidosauria; Squamata; Scleroglossa; Serpentes;
            Colubroidea; Elapidae; Elapinae; Naja.
REFERENCE   1  (residues 1 to 81)
  AUTHORS   Yeo,M.S., Jeyaseelan,K., Chung,M.C., Gopalakrishnakone,P., Tan,C.H.
            and Wong,H.A.
  TITLE     Molecular cloning of a cardiotoxin structural gene from Malayan
            spitting cobra (Naja naja sputatrix)
  JOURNAL   Toxicon 31 (1), 53-60 (1993)
  MEDLINE   93190317
  REMARK    SEQUENCE FROM N.A.
            TISSUE=VENOM GLAND
FEATURES             Location/Qualifiers
     source          1..81
                     /organism="Naja sputatrix"
     Protein         1..81
                     /gene="CTX"
                     /product="CARDIOTOXIN PRECURSOR"
     Region          1..21
                     /evidence=experimental
                     /region_name="Signal"
     Region          22..81
                     /evidence=experimental
                     /note="CARDIOTOXIN."
                     /region_name="Mature chain"
     Bond            bond(24,42)
                     /evidence=not_experimental
                     /bond_type="disulfide"
     Bond            bond(35,59)
                     /evidence=not_experimental
                     /bond_type="disulfide"
     Bond            bond(63,74)
                     /evidence=not_experimental
                     /bond_type="disulfide"
     Bond            bond(75,80)
                     /evidence=not_experimental
                     /bond_type="disulfide"
ORIGIN
        1 mktlllttvv vtivcldley tlkcnklvpl fyktcpagkn lcykmfmvat pkvpvkrgci
       61 dvcpkssllv kyvccntdrc n
//

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