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                                     NAD+
                            NADH


                                   Isocitrate dehydrogenase, NAD-linked

                                              IsocitrateNAD+

                             alpha-Ketoglutarate      Aconitase



                  alpha-Ketoglutarate dehydrogenase complex
           NADH              Isocitrate lyase

                                                             cis-Aconitate





                 Succinyl-CoA

                                                                 Aconitase

     GDP




          Succinyl-CoA synthetase


                                                                  Citrate
      GTP



               Succinate
                                                                    CoAGlyoxylate



                                                               Citrate synthase
                             Acetyl-CoA

  FAD(enzyme-bound)            Malate synthase

                                                             Acetyl-CoASuccinate dehydrogenase
                                                           Oxaloacetate

                                   CoA

                          Fumarate FADH2(enzyme-bound)

                                               Malate dehydrogenase, NAD-linked

                                                      NADHMalate

                                Fumarase

                                              NAD+