Enzyme: 2.7.1.11: 6-PHOSPHOFRUCTOKINASE.

Alignments: [R] = Report; [W] = Wide format; [WP] = Wide with Probe Info; [F] = FastA; [D] = corresponding DNA; [T] = Tree

10386.1: [R][W][WP][F][D]    6-phosphofructokinase aa phosphofructokinase platelet 1 555-609 type phosphohexokinase
448.29:  [R][W][WP][F][D][T] 1-phosphofructokinase

Pathways which use 2.7.1.11:

AGLCDLCT.CAT:                             'alpha'-D-glucose--(`R`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
AGLCLCTENT.CAT:                           'alpha'-D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_[Enterobacteriaceae]
AGLCLCT.CAT:                              'alpha'-D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
AGLCLACPLMCYT.CAT:                        'alpha'-D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_plasma_membrane)
AGLCPYRPLMCYT.CAT:                        'alpha'-D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_plasma_membrane)
AGLCLCTCAPACTLPPPIATP.CAT:                'alpha'-D-glucose--(`S`)-lactate_catabolism_(carbamoyl_phosphate,_acetyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
AGLCETL.CAT:                              'alpha'-D-glucose--ethanol_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
AGLCPYR.CAT:                              'alpha'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)
AGLCPYRENT.CAT:                           'alpha'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_[Enterobacteriaceae]
AGLCETLCYTPAR.CAT:                        'alpha'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_particle)
AGLCPYRCYTPAR.CAT:                        'alpha'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_particle)
AGLCPYRCAPACTLPPPIATP.CAT:                'alpha'-D-glucose--pyruvate_catabolism_(carbamoyl_phosphate,_acetyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
BGLCLCT.CAT:                              'beta'-D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
BGLCETL.CAT:                              'beta'-D-glucose--ethanol_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
BGLCPYR.CAT:                              'beta'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)
BGLCETLCYTPAR.CAT:                        'beta'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_particle)
BGLCPYRCYTPAR.CAT:                        'beta'-D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_particle)
BGLCPYRPLMCYT.CAT:                        'beta'-D-glucose_(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_plasma_membrane)
BGLCLACPLMCYT.CAT:                        'beta'-D-glucose_(`S`)-pyruvate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_plasma_membrane)
F6PLCT.CAT:                               D-fructose_6-phosphate--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
F6PPYR.CAT:                               D-fructose_6-phosphate--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)
GTLPPLGAPDHAPPLMCYT.CAT:                  D-galactitol(,periplasma)--D-glyceraldehyde_3-phosphate,_glycerone_phosphate_catabolism_(protein_`N`(''p')-phosphohistidine,_NAD('+),_ATP)_(plasma_membrane,_cytosol)
GLCEXTACAPPHATPNADADPAMPLIPCOAPLMCYT.CAT: D-glucose(,extracellular)--acetate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_AMP,_lipoamide,_CoA)_(plasma_membrane,_cytosol)
GLCEXTACAPLMCYT.CAT:                      D-glucose(,extracellular)--acetate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH,_NADP('+),_CoA)_(plasma_membrane,_cytosol)
GLCEXTATLCOAPPHATPNADADPAMPLIPCOAPLMCYT.ANA: D-glucose(,extracellular)--acetyl-CoA_anabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_AMP,_lipoamide,_CoA)_(plasma_membrane,_cytosol)
GLCEXTLCTPPHATPNADADPAMPNADHPLMCYT.CAT:   D-glucose(,extracellular)--lactate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_AMP,_NADH)_(plasma_membrane,_cytosol)
GLCEXTLCTPLMCYT.CAT:                      D-glucose(,extracellular)--lactate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)
GLCEXTLCTPLMCYTBPGI.CAT:                  D-glucose(,extracellular)--lactate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)_[(2`R`)-2,3-bisphosphoglycerate-independent]
GLCEXTOAAPPHATPNADADPPLMCYT.CAT:          D-glucose(,extracellular)--oxaloacetate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP)_(plasma_membrane,_cytosol)
GLCEXTOAAPPHATPNADADPNADLIPCOAPLMCYT.CAT: D-glucose(,extracellular)--oxaloacetate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_lipoamide,_CoA)_(plasma_membrane,_cytosol)
GLCEXTPYRPLMCYT.CAT:                      D-glucose(,extracellular)--pyruvate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)
GLCEXTPYRPLMCYTBPGI.CAT:                  D-glucose(,extracellular)--pyruvate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)_[(2`R`)-2,3-bisphosphoglycerate-independent]
GLCPPLBDOLPLMCYT.CAT:                     D-glucose(,periplasma)--(`R,R`)-butane-2,3-diol_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)
GLCPPLACAPLMCYT.CAT:                      D-glucose(,periplasma)--acetate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA)_(periplasma,_cytosol)
GLCPPLACNCO2BUTPLMCYT.CAT:                D-glucose(,periplasma)--acetone,_CO(,2)_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA)_(butanoate-dependent)_(plasma_membrane,_cytosol)
GLCPPLACNCO2PLMCYT.CAT:                   D-glucose(,periplasma)--acetone,_CO(,2)_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA)_(plasma_membrane,_cytosol)
GLCPPLBUTPLMCYT.CAT:                      D-glucose(,periplasma)--butanoate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA,_NADPH,_NADH)_(plasma_membrane,_cytosol)
GLCPPLBOLPLMCYT.CAT:                      D-glucose(,periplasma)--butanol_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA,_NADPH,_NADH)_(plasma_membrane,_cytosol)
GLCPPLETLPLMCYT.CAT:                      D-glucose(,periplasma)--ethanol_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_NADH)_(plasma_membrane,_cytosol)
GLCPPLLCTPLMCYT.CAT:                      D-glucose(,periplasma)--lactate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP,_NADH)_(plasma_membrane,_cytosol)_[Enterobacteriaceae]
GLCPPLPYRPLMCYT.CAT:                      D-glucose(,periplasma)--pyruvate_catabolism_(protein_III('Glc)_`N`(''p')-phosphohistidine,_ATP,_NAD('+),_ADP)_(plasma_membrane,_cytosol)
GLCPPLLCTPLMCYTENT.CAT:                   D-glucose(,periplasma)--pyruvate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP)_(plasma_membrane,_cytosol)_[Enterobacteriaceae]
GLCPPLPYRPLMCYTENT.CAT:                   D-glucose(,periplasma)--pyruvate_catabolism_(protein_III('Glc)_`N`(''pi')-phosphohistidine,_ATP,_NAD('+),_ADP)_(plasma_membrane,_cytosol)_[Enterobacteriaceae]
GLCDLCT.CAT:                              D-glucose--(`R`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
GLCLCTENT.CAT:                            D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_[Enterobacteriaceae]
GLCLCT.CAT:                               D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
GLCLCTV2712BPGI.CAT:                      D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)_[via_EC_2.7.1.2,_(2`R`)-2,3-bisphosphoglycerate-independent]
GLCLCTV2712.CAT:                          D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)_[via_EC_2.7.1.2]
GLCLCTPLMCYT.CAT:                         D-glucose--(`S`)-lactate_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_plasma_membrane)
GLCLCTATPPPI.CAT:                         D-glucose--(`S`)-lactate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP)_(cytosol)
GLCLCTATPPPIV5422.CAT:                    D-glucose--(`S`)-lactate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP,_NADH)_(cytosol)_[via_EC_5.4.2.2]
GLCLCTACTLPPPIATP.CAT:                    D-glucose--(`S`)-lactate_catabolism_(acetyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
GLCLCTCAPATPPPI.CAT:                      D-glucose--(`S`)-lactate_catabolism_(carbamoyl_phosphate,_ATP,_pyrophosphate,_NAD('+),_ADP)_(cytosol)
GLCLCTCAPPPIATP.CAT:                      D-glucose--(`S`)-lactate_catabolism_(carbamoyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
GLCPYRCAPACTLPPPIATP.CAT:                 D-glucose--(`S`)-pyruvate_catabolism_(carbamoyl_phosphate,_acetyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
GLC3PGAGLS.CAT:                           D-glucose--3-phospho-D-glycerate_catabolism_(ATP,_NAD('+),_ADP)_(glycosome)
GLC3PGCPS.CAT:                            D-glucose--3-phospho-D-glycerate_catabolism_(ATP,_NADP('+),_ADP)_(chloroplast_stroma)
GLCACA.CAT:                               D-glucose--acetate_catabolism_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA)_(cytosol)
GLCACATPPPINADADPLIPCOA.CAT:              D-glucose--acetate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP,_lipoamide,_CoA)
GLCACNCO2.CAT:                            D-glucose--acetone,_CO(,2)_catabolism_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA)_(cytosol)
GLCACNCO2BUT.CAT:                         D-glucose--acetone,_CO(,2)_catabolism_(butanoate-dependent)_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA)_(cytosol)
GLCACTLCOATPPPINADADPLIPCOA.ANA:          D-glucose--acetyl-CoA_anabolism_(ATP,_pyrophosphate,_NAD('+),_ADP,_lipoamide,_CoA)
GLCBUT.CAT:                               D-glucose--butanoate_catabolism_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA,_NADPH,_NADH)_(cytosol)
GLCBOL.CAT:                               D-glucose--butanol_catabolism_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_acetyl-CoA,_NADPH,_NADH)_(cytosol)
GLCETL.CAT:                               D-glucose--ethanol_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol)
GLCETLCYTPAR.CAT:                         D-glucose--ethanol_catabolism_(ATP,_NAD('+),_ADP,_NADH)_(cytosol,_particle)
GLCETLVGLK.CAT:                           D-glucose--ethanol_catabolism_(via_glucokinase)_(ATP,_NAD('+),_ADP,_oxidized_ferredoxin,_CoA,_NADH)_(cytosol)
GLCLCTATPPPINADADPNADH.CAT:               D-glucose--lactate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP,_NADH)_(cytosol)
GLCPYR.CAT:                               D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)
GLCPYRV2712.CAT:                          D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_(via_EC_2.7.1.1.2)
GLCPYRENT.CAT:                            D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_[Enterobacteriaceae]
GLCPYRV2712BPGI.CAT:                      D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol)_[via_EC_2.7.1.2,_(2`R`)-2,3-bisphosphoglycerate-independent]
GLCPYRCYTMCIM.CAT:                        D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_mitochondrial_outer_membrane)
GLCPYRCYTPAR.CAT:                         D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_particle)
GLCPYRPLMCYT.CAT:                         D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(cytosol,_plasma_membrane)
GLCPYRGLSCYT.CAT:                         D-glucose--pyruvate_catabolism_(ATP,_NAD('+),_ADP)_(glycosome,_cytosol)
GLCPYRCPS.CAT:                            D-glucose--pyruvate_catabolism_(ATP,_NADP('+),_ADP)_(chloroplast_stroma)
GLCPYRATPPPIVG1P.CAT:                     D-glucose--pyruvate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP)_(cytosol)_[via_D-glucose_1-phosphate]
GLCPYRATPPPI.CAT:                         D-glucose--pyruvate_catabolism_(ATP,_pyrophosphate,_NAD('+),_ADP,_NADH)_(cytosol)
GLCPYRACTLPPPIATP.CAT:                    D-glucose--pyruvate_catabolism_(acetyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
GLCPYRCAPPPIATP.CAT:                      D-glucose--pyruvate_catabolism_(carbamoyl_phosphate,_pyrophosphate,_ATP,_NAD('+),_ADP)_(cytosol)
GSHPFKDS.ELT:                             glutathione--6-phosphofructokinase-disulfide_electron_transport_(cytosol)

Terry Gaasterland, Natalia Maltsev, Ross Overbeek, and Evgeni Selkov / gaasterland@mcs.anl.gov, maltsev@mcs.anl.gov , overbeek@mcs.anl.gov, evgeni@mcs.anl.gov].