Non-local hydrogen bond network connecting the distal loop (Ser 47 and Thr 50) and the diverging turn (Glu 30). Atomic coordinates were taken from the crystal structure of src SH3 domain with-in the context of the intact tyrosine kinase 2 . A coordinating water molecule may stabilize the interaction. Hydrogen bonding residues are shown in red; the two other residues in this region with high FF values (Gly 51 and Ala 45) are shown in magenta. (Figure adopted from Grantcharova and Baker, Nat. Struct. Biol., 1998, 5(8):714)

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Danny S. Hsu 1999-2000. All rights reserved.