Discussion
SNARE is a trimeric complex consists of syntaxin, synaptobrevin and SNAP-25.
It forms a four-helix-bundle with different characteristics form leucine-zipper and coiled-coil protein.
It can be cleaved by clostridal neurotoxins when the left-handed superhelix is loose.
The basic-charged C-terminus provides the cumulative electrostatic potential for membrane fusion.