PROSITE: PDOC00516 (documentation)


* Plant lipid transfer proteins signature *

Plant cells contain proteins, called lipid transfer  proteins  (LTP) [1,2,3],
which are able to facilitate  the transfer of  phospholipids  and other
lipids across membranes. These proteins, whose subcellular location is not
yet known, could play  a  major   role  in  membrane biogenesis by conveying phospholipids such as  waxes or cutin from their site of biosynthesis to membranes
unable to form these lipids.
¡@

Plant LTP's are  proteins  of  about 9 Kd (90 amino acids) which contain eight
conserved  cysteine residues  all  involved  in disulfide bridges, as shown in
the following schematic representation.
                     +-----------------------+
                     |     +------+           |
                     |     |      |            |     ****************
                    xCxxxxCxxxxxxCCxxxxxxxxCxCxxxxxxxxxxxCxxxxxxCxx
                                  |         |              |       |
                                  +--------|-------------+       |
                                           +--------------------+

'C': conserved cysteine involved in a disulfide bond.
'*': position of the pattern.

Consensus pattern:
¡@
           [LIVM]-[PA]-x(2)-C-x-[LIVM]-x-[LIVM]-x-[LIVMFY]-x-[LIVM]-
           [ST]-x(3)-[DN]-C-x(2)-[LIVM]
           [The two C's are involved in disulfide bonds]

-Sequences known to belong to this class detected by the pattern: ALL,  except
  for 5 sequences.
-Other sequence(s) detected in SWISS-PROT: NONE.

-Note: some  of  these  proteins  were originally thought to be alpha-amylase/
  protease inhibitors (PAPI).

-Last update: November 1997 / Pattern and text revised.