human MLH1 protein with MLH1 in M. musculus 
Identities = 651/760 (85%), Positives = 693/760 (90%), Gaps = 4/760 (0%)
Query: 1   MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ 60
           M+FVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKST+IQV+VKEGGLKLIQ
Sbjct: 1   MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQ 60

Query: 61  IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA 120
           IQDNGTGIRKEDLDIVCERFTTSKLQ+FEDLASISTYGFRGEALASISHVAHVTITTKTA
Sbjct: 61  IQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTA 120

Query: 121 DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVV 180
           DGKCAYRASYSDGKL+APPKPCAGNQGT ITVEDLFYNI TRRKALKNPSEEYGKILEVV
Sbjct: 121 DGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVV 180

Query: 181 GRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAF 240
           GRYS+HN+GISFSVKKQGETV+DVRTLPNA+TVDNIRSIFGNAVSRELIE+GCEDKTLAF
Sbjct: 181 GRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF 240

Query: 241 KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP 300
           KMNGYISNANYSVKKCIFLLFINHRLVES +LRKAIETVYAAYLPKNTHPFLYLSLEISP
Sbjct: 241 KMNGYISNANYSVKKCIFLLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISP 300

Query: 301 QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMV 360
           QNVDVNVHPTKHEVHFLHEESIL+RVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGE  
Sbjct: 301 QNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEAA 360

Query: 361 KXXXXXXXXXXXXXXDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQ--AIVTEDKTD 418
           +              DKVYA+QMVRTDSR+QKLDAFLQP+S  + SQPQ  A V   +T+
Sbjct: 361 RPTTGVASSSTSGSGDKVYAYQMVRTDSRDQKLDAFLQPVSSLVPSQPQDPAPVRGARTE 420

Query: 419 ISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSS--NPRKRHRXX 476
            S  RA ++DEEML LPAPAE AA++++LE ++   TS+ ++K  PTSS  + RKRHR  
Sbjct: 421 GSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHRED 480

Query: 477 XXXXXXXXXXRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNP 536
                      KEMTAAC PRRRIINLTSVLSLQEEI+E+ HE LRE+L NHSFVGCVNP
Sbjct: 481 SDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREILRNHSFVGCVNP 540

Query: 537 QWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESG 596
           QWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESG
Sbjct: 541 QWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESG 600

Query: 597 WTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIF 656
           WTE+DGPKEGLAEYIVEFLKKKAEMLADYFS+EIDEEGNLIGLPLLID+YVPPLEGLPIF
Sbjct: 601 WTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIF 660

Query: 657 ILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTV 716
           ILRLATEVNWDEEKECFESLSKECAMFYSIRKQYI EESTLSGQQS++PGS    WKWTV
Sbjct: 661 ILRLATEVNWDEEKECFESLSKECAMFYSIRKQYILEESTLSGQQSDMPGSTSKPWKWTV 720

Query: 717 EHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756
           EHI+YKA RSH+LPPKHFTEDGN+LQLANLPDLYKVFERC
Sbjct: 721 EHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC 760

human MLH1 protein with MLH1 in R. norvegicus
Identities = 639/758 (84%), Positives = 684/758 (89%), Gaps = 3/758 (0%)
Query: 1   MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ 60
           MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEM ENCLDAKST+IQVIV+EGGLKLIQ
Sbjct: 1   MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMTENCLDAKSTNIQVIVREGGLKLIQ 60

Query: 61  IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA 120
           IQDNGTGIRKEDLDIVCERFTTSKLQ+FEDLA ISTYGFRGEALASISHVAHVTITTKTA
Sbjct: 61  IQDNGTGIRKEDLDIVCERFTTSKLQTFEDLAMISTYGFRGEALASISHVAHVTITTKTA 120

Query: 121 DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVV 180
           DGKCAYRASYSDGKL+APPKPCAGNQGT ITVEDLFYNI TR+KALKNPSEEYGKILEVV
Sbjct: 121 DGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRKKALKNPSEEYGKILEVV 180

Query: 181 GRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAF 240
           GRYS+HN+GISFSVKKQGETV+DVRTLPNA+TVDNIRSIFGNAVSRELIE+GCEDKTLAF
Sbjct: 181 GRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF 240

Query: 241 KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP 300
           KMNGYISNANYSVKKCIFLLFINHRLVES +L+KAIE VYAAYLPKNTHPFLYL LEISP
Sbjct: 241 KMNGYISNANYSVKKCIFLLFINHRLVESAALKKAIEAVYAAYLPKNTHPFLYLILEISP 300

Query: 301 QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMV 360
           QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGE V
Sbjct: 301 QNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEAV 360

Query: 361 KXXXXXXXXXXXXXXDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDIS 420
           K              DKV+A+QMVRTDSR+QKLDAF+QP+S+ L SQPQ  V  ++T+ S
Sbjct: 361 KSTTGIASSSTSGSGDKVHAYQMVRTDSRDQKLDAFMQPVSRRLPSQPQDPVPGNRTEGS 420

Query: 421 SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSE-MSEKRGPTS-SNPRKRHRXXXX 478
             +A Q+D+E+ ELPAP E AA + SLE ++  G SE ++ +R P+S  + RKRH     
Sbjct: 421 PEKAMQKDQEISELPAPMEAAADSASLERESVIGASEVVAPQRHPSSPGSSRKRHPEDSD 480

Query: 479 XXXXXXXXRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQW 538
                   RKEMTAAC PRRRIINLTSVLSLQEEIN++GHE LREML NH+FVGCVNPQW
Sbjct: 481 VEMMENDSRKEMTAACYPRRRIINLTSVLSLQEEINDRGHETLREMLRNHTFVGCVNPQW 540

Query: 539 ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWT 598
           ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRL EPAPLFD AMLALDSPESGWT
Sbjct: 541 ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLPEPAPLFDFAMLALDSPESGWT 600

Query: 599 EEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFIL 658
           EEDGPKEGLAEYIVEFLKKKA+MLADYFS+EIDEEGNLIGLPLLID+YVPPLEGLPIFIL
Sbjct: 601 EEDGPKEGLAEYIVEFLKKKAKMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIFIL 660

Query: 659 RLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEH 718
           RLATEVNWDEE ECFESLSKECA+FYSIRKQYI EES LSGQQS++PGS    WKWTVEH
Sbjct: 661 RLATEVNWDEE-ECFESLSKECAVFYSIRKQYILEESALSGQQSDMPGSPSKPWKWTVEH 719

Query: 719 IVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756
           I+YKA RSH+LPPKHFTEDGN+LQLANLPDL KVFERC
Sbjct: 720 IIYKAFRSHLLPPKHFTEDGNVLQLANLPDLCKVFERC 757

human MLH1 protein with MLH1 in D. melanogaster
Query: 6   GVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNG 65
           GVIR+LDE VVNRIAAGE+IQRPANA+KE++EN LDA+ST IQV VK GGLKL+QIQDNG
Sbjct: 8   GVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNG 67

Query: 66  TGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCA 125
           TGIR+EDL IVCERFTTSKL  FEDL+ I+T+GFRGEALASISHVAH++I TKTA  KC 
Sbjct: 68  TGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCG 127

Query: 126 YRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSV 185
           Y+A+Y+DGKL+  PKPCAGNQGT I +EDLFYN+  RR+AL++P+EE+ ++ EV+ RY+V
Sbjct: 128 YKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAV 187

Query: 186 HNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGY 245
           HN  + F+++KQG+    +RT   +S  +NIR I+G A+S+EL+E    D+   F+    
Sbjct: 188 HNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSHRDEVYKFEAECL 247

Query: 246 ISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDV 305
           I+  NYS KKC  LLFIN RLVEST+LR +++++YA YLP+  HPF+Y+SL + PQN+DV
Sbjct: 248 ITQVNYSAKKCQMLLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDV 307

Query: 306 NVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEMVKXXXX 365
           NVHPTKHEVHFL++E I++ ++Q +E++LLGSN++R ++ Q  LPG   P  +  +    
Sbjct: 308 NVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYKQLRLPG--APDLDETQ---- 361

Query: 366 XXXXXXXXXXDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRAR 425
                      ++Y  +MVRTDS EQKLD FL PL K  S    +   E         A 
Sbjct: 362 -----LADKTQRIYPKEMVRTDSTEQKLDKFLAPLVKSDSGVSSSSSQE---------AS 407

Query: 426 QQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHRXXXXXXXXXXX 485
           +  EE   + A                                  K+ R           
Sbjct: 408 RLPEESFRVTAA---------------------------------KKSREVRLSSVLDMR 434

Query: 486 XRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQT 545
            R E   +   R  + NL  V  + E      HE    M +  SF               
Sbjct: 435 KRVERQCSVQLRSTLKNLVYVGCVDERRALFQHETRLYMCNTRSF--------------- 479

Query: 546 KLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKE 605
                     SEELFYQ +IY+F N   + +S P PL +L +L+L+S  +GWT EDG K 
Sbjct: 480 ----------SEELFYQRMIYEFQNCSEITISPPLPLKELLILSLESEAAGWTPEDGDKA 529

Query: 606 GLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRLATEVN 665
            LA+   + L KKA ++ +YF L I E+G L  LP L+  + P +  LP+++LRLATEV+
Sbjct: 530 ELADGAADILLKKAPIMREYFGLRISEDGMLESLPSLLHQHRPCVAHLPVYLLRLATEVD 589

Query: 666 WDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALR 725
           W++E  CFE+  +E A FY+              Q     G+     +WT+EH+++ A +
Sbjct: 590 WEQETRCFETFCRETARFYA--------------QLDWREGATAGFSRWTMEHVLFPAFK 635

Query: 726 SHILPPKHFTEDGNILQLANLPDLYKVFERC 756
            ++LPP    +   I +L NLP LYKVFERC
Sbjct: 636 KYLLPPPRIKD--QIYELTNLPTLYKVFERC 664