apo trp repressor

ID number:1RCS
Author:D.ZHAO,Z.ZHHENG
How many residues in one monomer:108
How many cofactors in whole complex:0


holo trp repressor

ID number:1WRS
Authors:D.ZHAO,Z.ZHHENG
How many residues in one monomer:108
How many cofactors in whole complex:1


complex molecule

ID number:1TRR
Authors:C.L.LAWSON
How many residues in one monomer:108
How many cofactors in whole complex:4


Trp repressor , a dimer of 108-residue polypeptide chains. When tryptophan is plentiful, trp repressor binds two trp equivaents and associates with the trp operator that is located within the trp promoter. Trp repressor binding exludes RNA polymerase from the promotor , preventing transcription of the trp operon. When trp becomes limiting, repressor is lifted because trp repressor lacking bound trp has a lowered affinity for the trp promotor.


arc repressor

ID number:1PAR
Authors:J.F.SCHILDBACH,M.E.MILLA,P.D.JEFFREY,B.E.RAUMANN,R.T.SAUER
Resolution: 2.4A

the DNA sequences of the Arc operator

Chain F  aatgatagaa gcactctact at
Chain E  tatagtagag tgcttctatc at

distance between hydrogen bonds

Gln9-A18: 3.14A red Asn11-C16: 3.15A white Arg13-G8: 2.67A purple