The crystal structures of Bc-Csp and Bs-CspB reveal that both have virtually identical backbone conformation.
Bacillus caldolyticus Csp
(Bc-Csp)-
Thermophilic
(right) Tm= 77.3 oC
Bacillus subtilis Csp (Bs-Csp)--
Mesophilic
(left) Tm= 49 oC
Both proteins unfold reversibly in two-state reaction.
