3DB Atlas for 1KWA
1KWA Kinase date Jan 16, 1998
title Human Casklin-2 Pdz Domain
authors D.L.Daniels, A.R.Cohen, J.M.Anderson, A.T.Brunger
compound source
Molecule: Hcasklin-2 Protein
Chain: A, B
Fragment: Pdz Domain
Synonym: Hcask, Glgf Repeat, Dhr
Engineered: Yes
Biological_unit: Monomer
 Organism_scientific: Homo Sapiens
Organism_common: Human
Organ: Liver
Cellular_location: Membrane-Associated
Plasmid: Pget-2t
Gene: Hcask
Expression_system: Escherichia Coli
Expression_system_strain: Dh5 Alpha
Expression_system_cellular_location: Cytoplasm
Expression_system_vector: Pgex-2t
Expression_system_plasmid: N-Terminal Gst Fusion, Amp Resistant;
Other_details: Cloned From A Cdna Liver Library
symmetry Space Group: C 2 2 21
R_factor 0.251
crystal
cell
length a length b length c angle alpha angle beta angle gamma
40.800 97.000 92.000 90.00 90.00 90.00
method X-Ray Diffractionresolution 1.93 Å
ligand SO4
note is a representative structure
Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] [Save to disk]
  • LPC: Ligand-Protein Contacts for 1KWA
  • CSU: Contacts of Structural Units for 1KWA
  • Likely Quarternary Molecular Structure file(s) for 1KWA
  • Structure Factors in CIF format (r1kwasf.ent.Z), size 122 Kb
  • Retrieve 1KWA in mmCIF format
    • View 1KWA in 3D
  • MDL's Chemscape Chime (Install Chime freeware) This is good for easiest viewing of basic structure.
  • RasMol (Install RasMol freeware) Here's help on how to use RasMol.
    • Visual 3D analysis of 1KWA
  • STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure.
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
    • Structure-derived information
  • scop (Structural Classification of Proteins)
  • Domain Definition for 1kwa from 3Dee ( The Database of Protein Domain Definitions )
  • Class (fold), Architecture (subfold), Topology, Homologous superfamily: CATH
  • Summaries and structural analyses of PDB data files: PDBSum
    • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1kwa_A] [1kwa_B]
    • Other resources with information on 1KWA
  • MMDB (Entrez's Structure Database)
    • Still Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

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