Primary Adult Rat Hepatocyte Cultures(Koide et al., BBRC, 1989)

Surface Coatings

• Collagen

• Glycoprotein

• Proteoglycan

Activity

Monolayer > Spheroid

Cell configuration

• Monolayer

• Multilayer islands

• Spheroids

Tissue-Specific Functions

Spheroid > Monolayer

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