Adrenal chromaffin cells on microcarriers exhibit enhanced long-term functional effects when implanted into the mammalian brain (Cherksey et al., 1996) Intrastratal transplantation of rat adrenal chromaffin cells seeded on microcarrier beads promote long-term functional recovery in hemiparkinsonian rats (Borlongan et al., 1998)
Attachment to microcarriers enhances the long-term viability of an implant into the brain (< 3 months „_ 8-12 months).