3DB Atlas for 1QWE
1QWE Complex (Signal Transduction Peptide) date Nov 09, 1995
title C-Src Sh3 Domain Complexed With Ligand App12
authors S.Feng, C.Kasahara, R.J.Rickles, S.L.Schreiber
compound source
Molecule: Tyrosine-Protein Kinase Transforming Protein Src
Chain: A
Fragment: Sh3 Domain
Synonym: P60-Src
Ec: 2.7.1.112
Engineered: Yes
 Organism_scientific: Avian Sarcoma Virus
Expression_system: Gst-Fusion
Expression_system_plasmid: Pgex-2t
Expression_system_gene: Chicken

Molecule: Ala-Pro-Pro-Leu-Pro-Pro-Arg-Asn-Arg-Pro-Arg-Leu
Chain: B
Synonym: App12
Engineered: Yes
Synthetic: Yes
methodNMR, Minimized Average Structure
Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] [Save to disk]
  • Likely Quarternary Molecular Structure file(s) for 1QWE
  • Retrieve 1QWE in mmCIF format
    • View 1QWE in 3D
  • MDL's Chemscape Chime (Install Chime freeware) This is good for easiest viewing of basic structure.
  • RasMol (Install RasMol freeware) Here's help on how to use RasMol.
    • Visual 3D analysis of 1QWE
  • STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure.
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
  • GRASS (Graphical Representation and Analysis of Structure Server)
    • View 1QWE in 2D
  • Topology of domains/folds: Chain: A from TOPS (The Atlas of protein topology cartoons )
    • Structure-derived information
  • Classification of representative domains in scop (Structural Classification of Proteins)
    - Domain d1qwea_, region a [rasmolscript] [script source]
  • Kinase (Protein Kinase Database Project)
  • Domain Definition for 1qwe from 3Dee ( The Database of Protein Domain Definitions )
  • Class (fold), Architecture (subfold), Topology, Homologous superfamily: CATH
  • Summaries and structural analyses of PDB data files: PDBSum
    • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1qwe_A] [1qwe_B]
  • SWISS-PROT database: [SRC_CHICK]
  • Alignments of the sequence of 1QWE with the sequences similar proteins can be viewed for classification [SRC_CHICK] at ProtoMap. Click on "Neighbors List", then on the "See Alignments" button below the list.
  • A sequence distance tree ("phylogenetic tree") can be viewed for 1ACL's classification [SRC_CHICK] at ProtoMap. Click on the Cluster number.
    • Other resources with information on 1QWE
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
    • Still Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

    • You may enter another PDB ID code
    Go [Back], to the [PDB Lite page], to the [3DB Browser page] or to the [PDB Home page]