At AMDL,
California
Dinosaurs Chin ID: u881611
Department of life science, NTHU
The DR-70 is an antigen that target the proteinase
cathepsin B, which is one kind of fibrinogen degradation protein (FDP) as
plasiminogen activator that were normally secreted by tumor cell for fibrinose
lysis. The general structure of cathepsin B is found at PDB protein database:
They provide all stable and ready-to-use reagents for this ELISA format
convenient.
The DR-70 test procedure. |
The DR-70 Reactions. |
From their publish, the Journal of Immunoassay, 19(1), 63-72
(1998), this procedure has specificity more than 95% and sensitivity up to
83.8%.
From the information in the booklet as their publication, they have
said that some of the reagents contain human blood components that may transmit
infection and no known test method can offer complete assurance for not being
so.
Still there were many warnings in this booklet that may be the
limitation of this drug, and most of which were about the treatment of the
reagents.
AMDL, INC.
2492 Walnut Ave., Suite 100
Tustin, CA 92680-6953
USA
CALL (714) 505-4460
FAX (714) 505-4464
http://www.amdl.com
http://www.amdl.com/broch.html
as the page that introduce DR-70
http://www.dr-70.com.tw/index-main.html the website
of 華大生化科技 that
about DR-70, containing detail introduction of which in Chinese form.
http://www.rcsb.org/pdb/
Structure Explorer - 1HUC
|
Title |
The refined
2.15 A X-ray crystal structure of human liver cathepsin B: the structural
basis for its specificity. |
Classification |
Thiol
Protease |
Compound |
Cathepsin B
(E.C. 3.4.22.1) |
Exp.
Method |
X-ray
Diffraction |