4. Compare human MLH1 protein with MLH1 in M. musculus, R. norvegicus and D. melanogaster. Give the pairwise alignment and % of sequence smility.

M. musculus:


gi|13878583|sp|Q9JK91|MLH1_MOUSE DNA MISMATCH REPAIR PROTEIN MLH1 (MUTL PROTEIN HOMOLOG 1)
gi|7595954|gb|AAF64514.1|AF250844_1 (AF250844) MutL homolog 1 protein [Mus musculus]
Length = 760

Identities = 651/760 (85%), Positives = 693/760 (90%), Gaps = 4/760 (0%)

R. norvegicus


>gi|13591989|ref|NP_112315.1| (NM_031053) mismatch repair protein [Rattus norvegicus]
gi|13878571|sp|P97679|MLH1_RAT DNA MISMATCH REPAIR PROTEIN MLH1 (MUTL PROTEIN HOMOLOG 1)
gi|1724118|gb|AAB38506.1| (U80054) mismatch repair protein [Rattus norvegicus]
Length = 757

Score = 1289 bits (3336), Expect = 0.0
Identities = 639/758 (84%), Positives = 684/758 (89%), Gaps = 3/758 (0%)

D. melanogaster

>gi|7304079|gb|AAF59117.1| (AE003838) Mlh1 gene product [Drosophila melanogaster]
Length = 664

Score = 615 bits (1586), Expect = e-175
Identities = 335/751 (44%), Positives = 453/751 (59%), Gaps = 94/751 (12%)

pairwise alignment 可以在上個問題的所在網頁中看到.