| 1. |
To use ORF
finder to translate DNA sequence to protein sequence in all reading
frames. |
| 2. |
To use blastn,
blastp, CD search and blast 2 sequence programs for searching and
comparison. |
| -Deadline-
11/06/2001 |
| |
 |
Compare
MLH1 (answer of assignment 2.6) and mutS (answer of 2.7)
sequence. |
|
Translate
the above two gene sequences to protein sequences. |
|
Perform
protein sequence homology searching for MLH1 in GenBank. Give the
10 highest hits. |
|
Compare
human MLH1 protein with MLH1 in M. musculus, R. norvegicus
and D. melanogaster. Give the pairwise alignment and % of
sequence smility. |
|
Search
the conserve domain (CD) for MLH1. Give the position of the CD,
name of CD and Pfam ID number. |
|
Show
multiple alignment of MLH1 conserve domain with 5 sequences from
the top of the CD alignment. |
