Multiple Sequence Alignment of MLH1 protein.
- To do Multiple Sequence Alignment in Biology Workbench
- To draw phylogenetic tree from alignment
- Deadline - 12/06/2001
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Add MLH1_Human protein to the Biology
Workbench. Predict its secondary structure by GOR4. |
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Do a homology searching of MLH1_Human
in Genpept Full Release Database. Import MLH1-like protein of C.
elegans, S. cerevisiae, D. melanogaster, R. norvegicus and M. musculus
to your workbench. Run CLUSTALW to get multiple sequence alignment
for these six proteins. |
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Perform BOXSHADE program to get a color-coded
plot for the results of question 2. |
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Draw rooted phylogenetic
tree for these proteins. |
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