1. 1. Search human Mlh1 or its homologous proteins in Protein Data Bank (PDB) database. You just need to search for protein structure, do not find complex structure. Give its (a) ID number, (b) Name of the molecule, (c) experimental method for structure determination and (d) Resolution of the structure.
Ans: (a)1BKN (b)mutl (c)x-ray diffraction (d)2.90
2. Show its structure in ribbons form (400x400).
3. Give the structural informations of this PDB file (a) number of protein chains,
(b) number of helix in one protein chain, (c) the first and last residues in
the helix 6 .
Ans: (a)2, A and B (b)A¦³11Ó B¦³10Ó (c)THR and ALA
4. Give the Class, Fold, Superfamily and Family of this protein in Structural
Classification of Proteins (SCOP).
Ans: there are 2 kinds. Press link please.
5. (a) Show Ramachandran plot for this PDB file. (b) How many residues are in
the most favoured regions of Ramachandran plot?
Ans: (a)link (b) 379 link
