C-terminal domain and calcium ion binding

* The C-terminal domain (residues256-370) is an eight-stranded
     antiparallel £]-sandwich with an immunoglobin-like fold.
* Calcium binds specifically to the C-terminal domain and induces
     a conformation change.(CD)
* Implications of the structural analogy with C2 domains.
 

    a. £\-toxin C-terminal domain is shown in blue and human pancreatic lipase (HPL) is yellow.

    b. The N-terminal domain of soybean lipoxygenase-1(1LO).


    c. Two C2 domain of synaptotagmin I
    d. The C2 domain of phosphoinositide-specific phospholipase C£_1(PI-PLC)