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Biochemistry 2003 Jun 24;42(24):7457-66.
Peripheral binding mode and penetration depth of cobra cardiotoxin on phospholipid membranes as studied by a combined FTIR and computer simulation approach.
Huang WN, Sue SC, Wang DS, Wu PL, Wu WG. |
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J Biol Chem 2003 Jun 13;278(24):21980-8
Structural basis of membrane-induced cardiotoxin A3 oligomerization.
Forouhar F, Huang WN, Liu JH, Chien KY, Wu WG, Hsiao CD. |
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J Biol Chem 2002 Jan 25;277(4):2666-73
Heparin binding stabilizes the membrane-bound form of cobra cardiotoxin.
Sue SC, Chien KY, Huang WN, Abraham JK, Chen KM, Wu WG. |
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Biochemistry 2001 Oct 30;40(43):12782-94
Dynamic characterization of the water binding loop in the P-type cardiotoxin: implication for the role of the bound water molecule.
Sue SC, Jarrell HC, Brisson JR, Wu WG. |
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Biochemistry 2001 Sep 4;40(35):10436-46
Structures of heparin-derived disaccharide bound to cobra cardiotoxins: context-dependent conformational change of heparin upon binding to the rigid core of the three-fingered toxin.
Sue SC, Brisson JR, Chang SC, Huang WN, Lee SC, Jarrell HC, Wu W. |
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Biochemistry 1998 Mar 31;37(13):4527-34
Glycosaminoglycans bind to homologous cardiotoxins with different specificity.
Vyas KA, Patel HV, Vyas AA, Wu W
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Biochemistry 1997 Aug 12;36(32):9826-36
Action of Taiwan cobra cardiotoxin on membranes: binding modes of a beta-sheet polypeptide with phosphatidylcholine bilayers.
Sue SC, Rajan PK, Chen TS, Hsieh CH, Wu W
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Biophys J 1997 Aug;73(2):870-7
Membrane packing geometry of diphytanoylphosphatidylcholine is highly sensitive to hydration: phospholipid polymorphism induced by molecular rearrangement in the headgroup region.
Hsieh CH, Sue SC, Lyu PC, Wu WG
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J Biol Chem 1997 Apr 11;272(15):9661-70
Analysis of binding of cobra cardiotoxins to heparin reveals a new beta-sheet heparin-binding structural motif.
Vyas AA, Pan JJ, Patel HV, Vyas KA, Chiang CM, Sheu YC, Hwang JK, Wu Wg
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Biochemistry 1997 Mar 4;36(9):2403-13
Crystal structure of cardiotoxin V from Taiwan cobra venom: pH-dependent conformational change and a novel membrane-binding motif identified in the three-finger loops of P-type cardiotoxin.
Sun YJ, Wu WG, Chiang CM, Hsin AY, Hsiao CD
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J Biol Chem 1997 Jan 17;272(3):1484-92
Heparin and heparan sulfate bind to snake cardiotoxin. Sulfated oligosaccharides as a potential target for cardiotoxin action.
Patel HV, Vyas AA, Vyas KA, Liu YS, Chiang CM, Chi LM, Wu Wg
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Biophys J 1996 Dec;71(6):3278-87
Structure and dynamics of primary hydration shell of phosphatidylcholine bilayers at subzero temperatures.
Hsieh CH, Wu WG
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Biochemistry 1996 Jul 16;35(28):9177-86
The role of acidic amino acid residues in the structural stability of snake cardiotoxins.
Chiang CM, Chang SL, Lin HJ, Wu WG
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Biochemistry 1996 Jul 16;35(28):9167-76
Conformational change and inactivation of membrane phospholipid-related activity of cardiotoxin V from Taiwan cobra venom at acidic pH.
Chiang CM, Chien KY, Lin HJ, Lin JF, Yeh HC, Ho PL, Wu WG
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Biophys J 1995 Dec;69(6):2521-30
Molecular order and hydration property of amine group in phosphatidylethanolamine and its N-methyl derivatives at subzero temperatures.
Hsieh CH, Wu WG
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Biophys J 1995 Jul;69(1):4-12
Solvent effect on phosphatidylcholine headgroup dynamics as revealed by the energetics and dynamics of two gel-state bilayer headgroup structures at subzero temperatures.
Hsieh CH, Wu WG
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Toxicon 1994 Dec;32(12):1679-83
Expression of glutathione S-transferase-cardiotoxin fusion protein in Escherichia coli.
Chi LM, Vyas AA, Rule GS, Wu WG
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J Biol Chem 1994 May 20;269(20):14473-83
Two distinct types of cardiotoxin as revealed by the structure and activity relationship of their interaction with zwitterionic phospholipid dispersions.
Chien KY, Chiang CM, Hseu YC, Vyas AA, Rule GS, Wu W
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J Biol Chem 1991 Jul 25;266(21):13602-6
Freezing of phosphocholine headgroup in fully hydrated sphingomyelin bilayers and its effect on the dynamics of nonfreezable water at subzero temperatures.
Wu WG, Chi LM, Yang TS, Fang SY
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J Biol Chem 1991 Feb 15;266(5):3252-9
Fusion of sphingomyelin vesicles induced by proteins from Taiwan cobra (Naja naja atra) venom. Interactions of zwitterionic phospholipids with cardiotoxin analogues.
Chien KY, Huang WN, Jean JH, Wu WG
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Biochim Biophys Acta 1991 Feb 11;1062(1):46-50
Mechanism of hemolysis of red blood cell mediated by ethanol.
Chi LM, Wu WG
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J Mol Biol 1991 Jun 20;219(4):591-2
Preliminary crystallographic analysis of cardiotoxin V with major fusion activity from Taiwan cobra (Naja naja atra) venom.
Chen CJ, Rose J, Hsiao CD, Lee TJ, Wu WG, Wang BC
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Biochim Biophys Acta 1990 Aug 24;1027(2):163-71
Biophysical correlates of lysophosphatidylcholine- and ethanol-mediated shape transformation and hemolysis of human erythrocytes. Membrane viscoelasticity and NMR measurement.
Chi LM, Wu WG, Sung KL, Chien S
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Biochim Biophys Acta 1990 Jul 24;1026(2):225-35
Comparisons of lipid dynamics and packing in fully interdigitated monoarachidoylphosphatidylcholine and non-interdigitated dipalmitoylphosphatidylcholine bilayers: cross polarization/magic angle spinning 13C-NMR studies.
Wu WG, Chi LM
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Biophys J 1990 Jun;57(6):1225-32
Effective bilayer expansion and erythrocyte shape change induced by monopalmitoyl phosphatidylcholine. Quantitative light microscopy and nuclear magnetic resonance spectroscopy measurements.
Chi LM, Wu WG
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