Publications (SCI full articles)

Chen, C.-W., Y.-C. Yen, D. R. Klopfenstein and O. I. Wagner*. 2011. Differential effects of dynactin and dynein on bidirectional movements of kinesin-3 KIF1A/UNC-104 and synaptic vesicles in C. elegans neurons. in revision *corresponding author (NSC 97-2311-B-007-006-MY3)

Tien, N.-W., G.-H. Wu, C.-C. Hsu, C.-Y. Chang and O. I. Wagner*. 2011. Tau/PTL-1 associates with kinesin-3 KIF1A/UNC-104 and affects the motor’s motility characteristics in C. elegans neurons. Neurobiol. Dis. 43:495-506 (PDF) [IF 5.121, Rank: Q1] *corresponding author (NSC 97-2311-B-007-006-MY3)

Hsu, C.-C., J. D. Moncaleano and O. I. Wagner*. 2011. Sub-cellular distribution of UNC-104(KIF1A) upon binding to adaptors as UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(liprin-a) in C. elegans neurons. Neuroscience 176:39-52 (PDF) [IF 3.215, Rank: Q2] *corresponding author (NSC 97-2311-B-007-006-MY3)

Wagner, O. I.*, A. Esposito, B. Köhler, C.-W. Chen, C.-P. Shen, G.-H. Wu, S. Mandalapu, D. Wenzel, F. S. Wouters and D. R. Klopfenstein*. 2009. Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans. Proc. Natl. Acad. Sci. U S A
106:19605-19610 (PDF) [IF 9.771, Rank: Q1, 13 citations] *corresponding authors (NSC 97-2311-B-007-006-MY3)

Wagner, O. I., S. Rammensee, N. Korde, Q. Wen, J.-F. Leterrier, P. A. Janmey. 2007. Softness, strength and self-repair in intermediate filament networks. Exp. Cell Res. 313:2228-2235 (PDF) [IF 3.609, Rank: Q2, 33 citations]

Dalhaimer, P., O. I. Wagner, J.-F. Leterrier, P. A. Janmey, H. Aranda-Espinoza and D. E. Discher. 2004. Flexibility transitions and looped adsorption of wormlike chains. J. Polym. Sci. B 43:280-286 (PDF) [IF 1.298, Rank: Q2, 5 citations]

Wagner, O. I., J. Ascano, M. Tokito, J.-F. Leterrier, P. A. Janmey and E. L. F. Holzbaur. 2004. The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol. Biol. Cell 15:5092-5100 (PDF) [IF 5.861, Rank: Q1, 41 citations]

Wagner, O. I.*, J. Lifshitz, P. A. Janmey, M. Linden, T. K. McIntosh and J.-F. Letterier. 2003. Mechanisms of mitochondria-neurofilament interactions. J. Neuroscience 23:9046-9058 (PDF) [IF 7.271, Rank: Q1, 72 citations] *corresponding author

Schindler, R., E. Weichselsdorfer, O. Wagner, D. Schmitz, and J. Bereiter-Hahn. 2001. Aldolase-localization in cultured cells: cell-type and substrate-specific regulation of cytoskeletal associations. Biochem. Cell Biol. 79:719-728 (PDF) [IF 2.992, Rank: Q2, 20 citations]

Wagner, O., P. Hofmann, D. Langer, H. Schüler, P. Dancker, and J. Bereiter-Hahn. 2001. Sound attenuation of polymerizing actin reflects supramolecular structures: viscoelastic properties of actin gels modified by cytochalasin, profilin and a-actinin.
Biochem. J.355:771-778 (PDF) [IF 5.016, Rank: Q1, 10 citations]

Wagner, O., J. Zinke, P. Dancker, W. Grill, and J. Bereiter-Hahn. 1999. Viscoelastic properties of f-actin, microtubules, f-actin/a-actinin and f-actin/hexokinase determined in microliter volumes with a novel non-invasive method. Biophys. J. 76:2784-2796 (PDF) [IF 4.218, Rank: Q1, 40 citations]

Conference Proceedings (SCI-indexed)

Wagner, O. I., A. Esposito, K. Shen, D. Wenzel, B. Köhler, F. Wouters and D. R. Klopfenstein. 2006. How the LAR-interacting protein SYD-2 both clusters and regulates motor activity of KIF1A/UNC-104 in C. elegans. Eur. J. Cell Biol.85:23S

Janmey, P.A., O. I. Wagner, C. Mullin and J. F. Leterrier. 2004 . Charge effects in neurofilament networks. J. Am. Chem. Soc. 228:37 U485 (PDF)

Dalhaimer P., O. Wagner, Janmey P., Discher D. and H. Aranda-Espinoza. 2003. Simulations of polymer adsorption: conversions for persistence length based on confinement dimensionality and lasso formation Biophys. J. 84:473A

Bereiter-Hahn, J., R. Schindler and O. Wagner. 2003. Modulation of actin polymerisation and mechanics with conventional and unconventional binding proteins. Comp. Biochem. Phys. A 134:109S (PDF)

Wagner, O. I., J. Lifshitz, T. McIntosh, P. A. Janmey and J.-F. Leterrier. 2002. Mitochondrial-Neurofilament (NF) interactions are regulated by NF-sidearms and mitochondrial membrane potential. Biophys. J. 82:346A

Bereiter-Hahn J., J. Flauaus, R. Schindler, O. Wagner and D. Schmitz. 2000. Control of mechanical properties of the actin-cytoskeleton by associations with glycolytic enzymes. Mol. Biol. Cell 11:427A

Wagner, O., and J. Bereiter-Hahn. 1996. The oscillating rod viscosimeter: A new method for simultaneously measurement of dynamic viscosity and velocity of sound in cytogels using nanometer strains. Eur. J. Cell Biol.69:469S

Abstracts and Bookchapters

Georges, P., O. Wagner, T. Yeung and P. A. Janmey. 2004. Biopolymer Networks and Cellular Mechanosensing. Gravitational and Space Biology Bulletin 17:45-50 (PDF)

Bereiter-Hahn, J., C. Blase, T. Kundu and O. Wagner. 2002. Cells as seen with the acoustic microscope. Acoustical Imaging, Volume 26, edited by Roman Gr. Maev, University of Windsor, Ontario, Canada (PDF)

Bereiter-Hahn, J., and O. Wagner. 2001. Characterization of cytogels using acousto-microscopy-based oscillating rod rheometry. In: Advanced nondestructive evaluation for structural and biological health monitoring, Tribikram Kundu, Editor, Proceedings of SPIE 4335:236-243 (PDF)

Wagner, O. 2000. Strukturelle Grundlagen und Mechanik von Zytogelen. Dissertation. J. W. Goethe-University, Frankfurt, Germany (PDF)

Bereiter-Hahn, J., J. Airas, S. Blum, G. Minaschek, A. K. Mittal, O. Wagner and H. Fasold. 1999. Reciprocal modulation of actin polymerization, cell motility and glycolytic enzyme activity. Endocytobiology 7:533-552

Oral presentations or posters at symposia

2010

• October 2010: European C. elegans Neurobiology Meeting, Heraklion, Greece
  Lecture (by O. I. Wagner): “ Regulation of the molecular motor UNC-104(KIF1A) in the nervous system of C. elegans".
• August 2010: The first Taiwan C. elegans meeting, Chi-Tou, Taiwan
  Lecture (by Chen C. W.): “ A functional role of dynein/dynactin subcomplexes on UNC-104 motility in the nervous system of C. elegans.” Chen, C. W., Y. C. Yen and O. I. Wagner.

• August 2010: The first Taiwan C. elegans meeting, Chi-Tou, Taiwan
  Lecture (by Tien N. W.): “ Protein with tau-like repeats (PTL-1) is a cargo for KIF1A/UNC-104 and regulates its transport characteristics". Tien, N. W., C. C. Hsu and O. I. Wagner.
• July 2010: 4th East Asia C. elegans Meeting, Tokyo Medical and Dental University, Tokyo, Japan
  Poster: “ Visualization of neuronal precursor interaction complex in C. elegans using the bimolecular fluorescence complementation assay.” Hsu, C. C., J. D. Moncaleano and O. I. Wagner.
• July 2010: 4th East Asia C. elegans Meeting, Tokyo Medical and Dental University, Tokyo, Japan
  Poster: “ LIN-2(CASK) interacts with and activates kinesin-3 UNC-104 in C. elegans nervous system.” Huang, Y. H., G. H. Wu and O. I. Wagner.
• July 2010: 4th East Asia C. elegans Meeting, Tokyo Medical and Dental University, Tokyo, Japan
  Poster: “ Mechanisms of UNC-104/dynein interactions in the nervous system of C. elegans.” Chen, C. W., Y. C. Yan and O. I. Wagner.
• May 2010: University of Osaka (Japan) and NTHU Joint Symposia, Hsinchu, Taiwan
  Lecture (by Hsu C. C.): “ Visualization of neuronal precursor interaction complex in C. elegans using the bimolecular fluorescence complementation assay.” Hsu, C. C., and O. I. Wagner.
• April 2010: Francis Crick Symposium on Neuroscience, Cold Spring Harbor Conferences Asia, Suzhou, China
  Poster: “ The effect of tau protein on kinesin-3 UNC-104 motility in C. elegans.” Tien, N. W., and O. I. Wagner.
• April 2010: Francis Crick Symposium on Neuroscience, Cold Spring Harbor Conferences Asia, Suzhou, China
  Poster: “ Regulation of kinesin-3 UNC-104 by the MAGUK-protein LIN-2.” Wu G. H., Y. H. Huang and O. I. Wagner.
• April 2010: Francis Crick Symposium on Neuroscience, Cold Spring Harbor Conferences Asia, Suzhou, China
  Poster: "Control of liprin-a/SYD-2 binding to KIF1A/UNC-104 by the RIM/UNC-10 protein in C. elegans." Shen C. P., C. Y. Chang and O. I. Wagner.
• March 2010: The 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan
  Poster: “Neuropathological features of C. elegans neurons as determined by atomic force microscope (AFM) .” Wang Z. N., C. T. Lin, C. H. Lee, G. H. Wu, O. I. Wagner, F. G. Tseng and R. L. Pan.

2009

• May 2009: University of Osaka (Japan) and NTHU Joint Symposia, Hsinchu, Taiwan
  Lecture (by Tien N. W.): “ The role of MAPs and NFs on UNC-104/KIF1A motility.” Tien, N. W., and O. I. Wagner.
• Jan. 2009: International Workshop on Nonlinear Dynamics in Biological Systems and Soft-matter Biophysics, Academia Sinica, Taipei, Taiwan
  Poster: “Flexural rigidity and persistence length of neuronal processes as a novel characteristic for describing neuropathological phenotypes . ” Tarasov, A. S., C. N. Wang, C. P. Shen, J. M. Chang, P. Gronat, P. C. A. Lizana and O. I. Wagner.
• Jan. 2009: TIMS (Univ. Tsukuba, Japan) & NTHU Joint Symposium: Nano and Bio-related Materials and Technology, NTHU, Hsinchu, Taiwan
  Poster: “Design of a bio-chip for identification and selection of neural stem cells from mixtures of various cell types. ” Tu, W. T., S. R. Yeh, H. Chen, O. I. Wagner, and F. G. Tseng.

2008

• Dec. 2008: Seminar of the Department of Electrical Engineering at the National Chi Nan University, Puli (Nantou), Taiwan
  Lecture (by O. I. Wagner): “Introduction to Biological Machines, Cell Mechanics and Nanotechnology. ” O. I. Wagner.
• Oct. 2008: 2008 Nanotechnology Conference at THU, Beijing, China
  Lecture (by O. I. Wagner): “Design of a bio-chip for identification and selection of neural stem cells from mixtures of various cell types. ” Tu, W. T., S. R. Yeh, O. I. Wagner, and F. G. Tseng.
• Aug. 2008: 24th Biology Summer Camp in Chi-Tou, Taiwan
  Lecture (by O. I. Wagner): “Regulation of molecular motors in the nervous system of C. elegans. ” Wu, G. H., C. P. Shen, N. W. Tien, C. W. Chen, D. R. Klopfenstein and O. I. Wagner.
• July 2008: NTHU Neuroscience Colloquium, Hsinchu, Taiwan
  Lecture (by Tien N. W.): “ Obstacles on the highway: tau, MAP1A and neurofilaments in Kinesin-3 regulation.” Tien, N. W., and O. I. Wagner.
• July 2008: NTHU Neuroscience Colloquium, Hsinchu, Taiwan
  Lecture (by Shen C. P.): “ The role of RIM(UNC-10) and CASK(LIN-2) in the KIF1A (UNC-104)/Liprin-alpha(SYD-2) complex.” Shen, C. P., and O. I. Wagner.
• May 2008: Bilateral Meeting of National University Singapore (NUS) and National Tsing-Hua University (NTHU), Hsinchu, Taiwan
  Lecture (by O. I. Wagner): “Regulation of molecular motors in the nervous system of C. elegans. ” Shen, C. P., G. H. Wu, C. W. Chen, L. S. Chien, D. R. Klopfenstein and O. I. Wagner.

2007

• Nov. 2007: 2007 NHRI-NTHU Joint Research Conference, Zhunan, Taiwan
  Lecture (by O. I. Wagner): “Regulation of molecular motors in the nervous system of C. elegans. ” Wu, G. H., C. P. Shen, C. W. Chen, L. S. Chien, D. R. Klopfenstein and O. I. Wagner.

2006

• Apr. 2006: Seminar of the Institute of Molecular and Cellular Biology, National Tsing-Hua University, Hsinchu, Taiwan
  Lecture (by O. I. Wagner): “LAR-interacting protein SYD-2 both clusters and regulates motor activity of KIF1A/UNC-104 in C. elegans. ” Wagner, O. I., A. Esposito, B. Köhler, D. Wenzel, K. Shen, F. S. Wouters, and D. R. Klopfenstein.
• Mar. 2006: Symposia of the German Society for Cellbiology, Braunschweig, Germany
  Poster: “How the LAR-interacting protein SYD-2 both clusters and regulates motor motility of UNC-104. ” Wagner, O. I., A. Esposito, B. Köhler, D. Wenzel, K. Shen, F. S. Wouters, and D. R. Klopfenstein.

2004

• Oct. 2004: 3rd Internat. Meeting on Protein and Membrane Transport, Max-Planck-Institute for Biophys. Chem., Göttingen, Germany
  Poster: “LAR-interacting protein SYD-2 may affect directionality of the kinesin motor UNC-104 in C. elegans .” Wagner, O. I., B. Köhler, and D. R. Klopfenstein.
• Aug. 2004: Molecular Events in Living Neurons, Max Planck Institute for Experimental Medicine, Göttingen , Germany
  Poster: “Effect of LAR-interacting protein SYD-2 on the kinesin motor UNC-104 and synaptic vesicle transport in C. elegans .” Wagner, O. I., B. Köhler, and D. R. Klopfenstein.
• Aug. 2004: 228th ACS National Meeting, Philadelphia, USA
  Lecture (by Janmey, P.A.): “Charge effects in neurofilament networks.” Janmey, P. A., Wagner, O. I., Mullin, C., and Leterrier, J. F.

2003

• Nov. 2003: 19th Annual Meeting of the American Society for Gravitational and Space Biology, Huntsville, USA
  Lecture (by Janmey, P. A.): “Biopolymer Networks and Cellular Mechanosensing.” Janmey, P. A., Georges, P., Wagner, O. I., and T. Yeung.
• Apr. 2003: Annual Main Meeting of the Society for Experimental Biology, Southampton, UK
  Lecture (by Bereiter-Hahn, J.): “Modulation of actin polymerisation and mechanics with conventional and unconventional binding proteins.” Bereiter-Hahn, J., R. Schindler, and O. Wagner.
• Mar. 2003: 47th Annual Meeting of the Biophysical Society, San Antonio, Texas, USA
  Poster: “Simulations of polymer adsorption: conversions for persistence length based on confinement dimensionality and lasso formation.” Dalhaimer P, O. Wagner, P. Janmey, D. Discher, and H. Aranda-Espinoza.

2002

• Sep. 2002: "Soft Matters" Laboratory for Research on the Structure of Matter, UPENN, USA
  Poster: “Cytoskeletal polymers and cellular organelles as seen by AFM .” Wagner, O. I., and P. A. Janmey.
• Jun. 2002: Seminar of the Institute for Medicine and Engineering, UPENN, USA
  Lecture (by O. I. Wagner): “Mitochondria-neurofilament (NF) interactions are regulated by mitochondrial membrane potential, NF-phosphorylation and NF-sidearms .” Wagner, O. I., J. Lifshitz, P. A. Janmey, M. Linden, T. K. McIntosh and J.-F. Letterier.
• Febr. 2002: 46th Annual Meeting of the Biophysical Society, San Francisco, California, USA
  Lecture (by O. I. Wagner): “Mitochondrial-Neurofilament (NF) interactions are regulated by NF-sidearms, NF-phosphorylation and mitochondrial membrane potential .” Wagner, O. I., J. Lifshitz, P. A. Janmey, and J.-F. Letterier.

2001

• Nov. 2001: 9th Annual Retreat and Symposium - The Role of the Cytoskeleton in Diseases, UPENN, USA
  Poster: “Mitochondrial-neurofilament (NF) interactions are regulated by NF-sidearms and mitochondrial membrane potential.” Wagner, O. I., P. A. Janmey, and J.-F. Letterier.
• Sep. 2001: 26th International Acoustical Imaging Symposium, Windsor, Canada
  Lecture (by Bereiter-Hahn, J.): “Cells as seen with the acoustic microscope.”Bereiter-Hahn, J., C. Blase, T. Kundu, H. Luers, and O. Wagner.
• Mar. 2001: SPIE 6th Annual Internat. Symposium on: NDE for Health Monitoring and Diagnostics, Newport Beach, USA
  Lecture (by Bereiter-Hahn, J.): “Characterization of cytogels using acousto-microscopy-based oscillating rod rheometry.” Bereiter-Hahn, J., and O. Wagner.

2000

• Dec. 2000: 40th American Society for Cell Biology Annual Meeting, San Francisco, USA
  Lecture (by Bereiter-Hahn, J.): “Control of mechanical properties of the actin-cytoskeleton by associations with glycolytic enzymes.” Bereiter-Hahn J., J. Flauaus, R. Schindler, O. Wagner and D. Schmitz.

1999

• Oct. 1999 : 1st Munich Symposium on Cell Dynamics, Martinsried , Germany (see Meeting report: Nature Cell Biol. 2000;2:E17-8)
  Poster: “Mechanical properties of polymerizing non-muscle und muscle actin and upon interaction with profilin, cytochalasin D and a-actinin.” Wagner, O., J. Zinke, P. Dancker, W. Grill, and J. Bereiter-Hahn.
• Oct. 1999: ACAS'99 "Mechanical Properties of Cells and Tissues", Augustusburg , Germany
  Lecture (by O. I. Wagner): “Mechanical properties of polymerizing non-muscle actin upon interaction with profilin.” Wagner, O., H. Schüler, U. Lindberg, and J. Bereiter-Hahn.

1998

• Apr. 1998: 3rd European Research Conference: "Biophysics of Cytoskeleton", Obernai , France
  Poster: “Viscoelastic properties of f-actin, microtubules, f-actin/a-actinin and f-actin/hexokinase determined in microliter volumes with a novel non-invasive method.” Wagner, O., J. Zinke, P. Dancker, W. Grill, and J. Bereiter-Hahn.
• Apr. 1998: 7th International Congress on Endocytobiology, Symbiosis and Biomedicine: "From Symbiosis to Eukaryotism", Freiburg , Germany
  Lecture (by Bereiter-Hahn, J.): “Reciprocal modulation of actin polymerization, cell motility and glycolytic enzyme activity.” Bereiter-Hahn, J., J. Airas, S. Blum, G. Minaschek, A. K. Mittal, O. Wagner and H. Fasold.
• Jan. 1998: Internat. Symposium on the Mechanics of Plants, Animals and Their Environments: Integrative Perspectives, Santa Barbara , USA
  Poster: “Determination of visco-elastic properties of cytogels in microliter volumes .” Wagner, O., J. Zinke, and J. Bereiter-Hahn.

1997

• Feb. 1997 : Symposia for Bionik, Jena , Germany
  Lecture (by O. I. Wagner): “Mechanics of Cytogels.” Wagner, O., J. Zinke, W. Grill, and J. Bereiter-Hahn.

1996

• Mar. 1996: Symposia of the German Society for Cellbiology, Hamburg, Germany
  Lecture (by O. I. Wagner): “The oscillating rod viscosimeter: A new method for simultaneous measurement of dynamic viscosity and velocity of sound in cytogels using nanometer strains.” Wagner, O., and J. Bereiter-Hahn.